Results 71 to 80 of about 76,451 (278)

Developmental Trauma as a Prognostic Factor for Later Psychotic Disorder in an Adolescent Clinical Cohort: A 20‐Year Follow Up Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background and Hypothesis Recent studies demonstrate that individuals who attend psychiatric services in adolescence, especially inpatient care, have an increased risk of psychotic disorders in adulthood. Given the extensive literature demonstrating a relationship between developmental trauma and psychosis, we investigated whether trauma ...
Valentina Kieseppä, Covadonga M. Díaz‐Caneja, Bart P. F. Rutten, Pirkko Riipinen, Sinan Gülöksüz, Ian Kelleher   +5 more
wiley   +1 more source

Total and Partial Sleep Deprivation in Clomipramine-Treated Endogenous Depressives [PDF]

, 1990
Improvement in depression after total sleep deprivation (TSD) is, as a rule, followed by relapse after subsequent ad libitum sleep. This study is addressed to the question of how nocturnal partial sleep following TSD affects this relapse.
Beersma, Domien,, Elsenga, Simon,, Beersma, Domien, Hoofdakker, Rutger H. van den,, Elsenga, Simon, Hoofdakker, Rutger H. van den   +5 more
core   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Manic symptoms in patients with depressive and/or anxiety disorders

, 2010
Background: Previous studies found that patients with depressive disorders frequently have lifetime manic symptoms or even an unrecognized bipolar disorder and that these patients have more severe illness.
Berg, B. van den, Nolen, W.A., Zitman, Frans G., Penninx, B.W.J.H., van den Berg, B., Zitman, F.G., Penninx, Brenda, van den Berg, Belinda, Nolen, Willem A.   +8 more
core   +1 more source

Modulation of calcium and potassium currents by lamotrigine [PDF]

, 1998
Actions of the new antiepileptic drug lamotrigine (LTG) were characterized using extracellular and whole cell patch clamp recordings from rat CAI and CA3 pyramidal cells in vitro.
Greene, Robert, Wegerer, Jörg von, Greene, Robert W., Grunze, Heinz, Walden, Jörg   +4 more
core   +1 more source

An investigation using cultured human cell lines, of the involvement of vanadium, cation transport and phosphatidylinositol in the aetiology of bipolar manic-depressive psychosis

, 2015
The symptoms, classification, occurrence and possible aetiologies of bipolar manic-depressive psychosis have been reviewed, with particular emphasis on the possible role of the vanadate ion (V5+) and cation transport in the illness.
Banks, Rosamonde Elizabeth, Naylor, Graham   +1 more
core  

Manic Depressive Illness in Adolescence and Childhood: Review and Case Report

, 1979
The literature on this topic from its inception by Kraepelin is reviewed. While Kraepelin and the French school always recognized juvenile mania, the Anglo-American school has no such unanimity of opinion.
Patrick G. Coll, Roger Bland
core   +1 more source

What makes a lonely child: environmental, health, and multimodal neuroimaging correlates of prospective loneliness in the ABCD study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Loneliness in childhood is a growing public health concern, yet early multilevel candidate risk and protective factors remain insufficiently mapped. Systematic investigation is essential to guide prevention and intervention during sensitive developmental periods.
Ting Yat Wong, Ting Sam Wong, Wai Kai Hou, Angel Nga Man Leung, Jie Xiao, Kenneth S. L. Yuen, Simon S. Y. Lui, Anqi Qiu, Tyler M. Moore, Ruben C. Gur   +9 more
wiley   +1 more source

Relating depressive and manic symptomatology to 1H-MRS spectra

Journal of Affective Disorders Reports
Background: Alterations in neurochemical levels are potential biomarkers of affective disorders and offer a window into illness etiology. Much of the research done to date limits focus to few metabolites and relies on dichotomous diagnoses.
Alexa Choquette, Alecia Dager, Małgorzata Marjańska, Molly Zatony, Godfrey D. Pearlson, David C. Glahn, Emma.E.M. Knowles   +6 more
doaj   +1 more source

Impact of mood on endothelial function and arterial stiffness in bipolar disorder

Heart and Mind, 2018
Background: Previous research on bipolar disorder demonstrates greater-than-expected vascular dysfunction later in the course of illness, proportionate to the cumulative burden of mood symptoms.
Samantha L Schmitz, Oluchi J Abosi, Jane E Persons, Christine A Sinkey, Jess G Fiedorowicz   +4 more
doaj   +1 more source