Results 51 to 60 of about 18,794 (253)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Nonlinear dimensionality reduction for the acoustic field measured by a linear sensor array [PDF]

open access: yesMATEC Web of Conferences, 2019
Dimensionality reduction is one of the central problems in machine learning and pattern recognition, which aims to develop a compact representation for complex data from high-dimensional observations.
Zhang Xinyao, Wang Pengyu, Wang Ning
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Depth-Aware Fashion Synthesis via Manifold-Aligned Multi-Modal Diffusion

open access: yesIEEE Access
Fashion synthesis faces challenges generating geometrically consistent garment imagery respecting three-dimensional structure and cross-modal alignment.
Ruoan Ren   +3 more
doaj   +1 more source

ManiDec: Manifold Constrained Low-Rank and Sparse Decomposition

open access: yesIEEE Access, 2019
Low-rank and sparse decomposition based image alignment has recently become an important research topic in the computer vision community. However, the reconstruction process often suffers from the perturbations caused by variations of the input samples ...
Jingjing Liu   +6 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Plant Leaf Recognition through Local Discriminative Tangent Space Alignment

open access: yesJournal of Electrical and Computer Engineering, 2016
Manifold learning based dimensionality reduction algorithms have been payed much attention in plant leaf recognition as the algorithms can select a subset of effective and efficient discriminative features in the leaf images.
Chuanlei Zhang   +2 more
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

A prediction method for dynamic multiobjective optimization based on joint subspace and correlation alignment

open access: yesComplex & Intelligent Systems
Dynamic multiobjective optimization is a significant challenge in accurately capturing changes in Pareto optimal sets (PS), encompassing both location and manifold changes. Existing approaches primarily focus on tracking changes in the location of the PS,
Guoping Li, Yanmin Liu, Xicai Deng
doaj   +1 more source

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