Results 101 to 110 of about 706,075 (298)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Main Stem Sink Manipulation in Wheat [PDF]

, 1989
Charles T. MacKown, David A. Van Sanford, Yong-Zhan Ma   +2 more
openalex   +1 more source

TrollsWithOpinion: A Dataset for Predicting Domain-specific Opinion Manipulation in Troll Memes

, 2021
Shardul Suryawanshi, Bharathi Raja Chakravarthi, Mihael Arčan, Suzanne Little, Paul Buitelaar   +4 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Multidimensional Manipulation of Photonic Spin Hall Effect with a Single‐Layer Dielectric Metasurface

, 2018
Siqi Li, Xingyi Li, Guoxi Wang, Sheng Liu, Lingxuan Zhang, Chao Zeng, Leiran Wang, Qibing Sun, Wei Zhao, Wenfu Zhang   +9 more
openalex   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

A White Light Spectral Interferometric Demodulation Method Based on Frequency Domain Solving and Model Matching

IEEE Photonics Journal
White-light interferometry (WLI) is widely used for thin-film thickness metrology due to its non-destructive and high-speed characteristics. Yet conventional data-processing pipelines struggle to balance accuracy and computational efficiency.
Yanfang Yang, Xiaolong Cheng, Yuliang Long, Wei Liu, Xinxiang Gong, Jinfeng Jiang, Yan Tang   +6 more
doaj   +1 more source

What is in a tool concept? Dissociating manipulation knowledge from function knowledge

, 2012
Frank E. Garcea, Bradford Z. Mahon
openalex   +2 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source