Results 111 to 120 of about 22,101 (225)
Antidesma montanum, an edible wild plant, shows notable nutraceutical and pharmacological potential. Methanol extract profiling (GC–MS) identified bioactive metabolites. In vitro, in vivo, and in silico studies demonstrated significant antidiabetic, anthelmintic, anxiolytic, antidepressant, and antidiarrheal activities, supported by strong molecular ...
Naureen Banu +9 more
wiley +1 more source
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta +2 more
wiley +1 more source
ABSTRACT Background Sarcopenia is characterized by progressive loss of muscle mass, strength and physical performance, yet current diagnostic tools are limited for practical and longitudinal monitoring. Extracellular vesicles (EVs) encapsulate various biomolecules, including proteins, nucleic acids, lipids and metabolites and have emerged as promising ...
Ji Yeon Kim +11 more
wiley +1 more source
From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez +3 more
wiley +1 more source
An integrated bioinformatic pipeline combining taxonomic, functional, and network analyses revealed host‐driven structuring of macroalgal microbiomes. Phaeophyceae hosted distinct epiphytic communities enriched in chemoheterotrophy and polysaccharide degradation, highlighting metabolic coupling, keystone taxa, and a standardized framework for ...
J. Z. Florez +9 more
wiley +1 more source
Graphical abstract shows fungal‐fungal co‐culture in food waste derived media with the scale‐up cultivation to produce alternative leather materials (Created in BioRender. Wijayarathna, E. R. K. B. (2026) https://BioRender.com/9iz8hh3). ABSTRACT Co‐culturing fungi offers a promising strategy for generating hybrid fungal biomass with structural and ...
E. R. Kanishka B. Wijayarathna +6 more
wiley +1 more source
3 years follow‐up study to a DBPC dose‐finding trial investigating subcutaneous immunotherapy with T502 in birch‐pollen induced allergic rhinoconjunctivitis. 154 birch‐pollen allergic adults received short‐course treatment of 10,000 mTU/mL of T502 for 2 years and were observed during the next season without treatment.
Ralph Mösges +15 more
wiley +1 more source
ABSTRACT Imlunestrant is a next‐generation, oral, selective estrogen receptor degrader approved for treating adults with estrogen receptor‐positive, human epidermal growth factor receptor 2‐negative, ESR1‐mutated advanced/metastatic breast cancer. Imlunestrant is metabolized partly by cytochrome P450 (CYP)3A4 oxidation and conjugation with glucuronic ...
Amita Datta‐Mannan +5 more
wiley +1 more source
Orchid genome evolution and trait innovation
Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng +8 more
wiley +1 more source

