Results 121 to 130 of about 37,734 (251)

Cyclin‐dependent kinase 4/6 (CDK4/6) inhibitor‐induced hepatotoxicity and its resolution: a study of seven cases

Histopathology, EarlyView.
CDK4/6 inhibitor‐induced liver injury represents a clinically significant and histologically distinctive form of drug‐induced hepatotoxicity, most commonly encountered with ribociclib. The predominant pattern is severe acute hepatocellular injury, frequently accompanied by lymphocytic cholangitis, a combination that, in the appropriate clinical context,
Sunayana Misra, Lisa Centeno, Dupinder Singh, Romil Saxena, Rifat Mannan   +4 more
wiley   +1 more source

Diatom mannan – a sulfated glycan shapes surface ocean microbiomes

Diatoms account for 20% of global photosynthesis and secrete up to 50% of their primary products as glycans. The fate of these glycans influences global ocean carbon budgets and exerts substantial selection pressure on the surrounding microbiome. However,
Krull, Joris
core   +1 more source

Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines

Immunology, EarlyView.
This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw, Aytenew Atnaf, Bantayehu Addis Tegegne, Abebe Fenta, Bantegzie Selabat, Temesgen Baylie, Yonatan Kindie, Zigale Hibstu Teffera, Mekuriaw Belayneh, Mohammed Jemal, Adane Adugna   +10 more
wiley   +1 more source

Low Allergic Sensitisation in Wheezing Children With Down Syndrome: A Case–Control Study

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Respiratory disorders are frequent in children with Down syndrome (DS), causing prolonged hospitalisations and increased healthcare system costs. Among these, recurrent wheezing is common in these children despite indications of lower rates of allergic sensitisation and asthma.
Francylene Malheiros Macedo da Cunha Rego, Geórgia Veras de Araújo Gueiros Lira, Emanuel Sávio Cavalcanti Sarinho, Patricia Gomes de Matos Bezerra, Marcilio Lins Aroucha, Igor Gabriel Araujo Medeiros, Decio Medeiros Peixoto   +6 more
wiley   +1 more source

ELUCIDATION OF THE STRUCTURE AND BIOSYNTHESIS OF WHEAT GRAIN MANNAN

, 2021
International audienceCereal grain cell walls are studied for their nutritional benefits (dietary fibre), their adverse effects on the digestive health of livestock such as poultry and pigs, and their effects on grain usage (bread making, pasta, brewing..
Voiniciuc, Catalin, Mitchell, Rowan,, Wilkinson, Mark,, Guillon, Fabienne, Alvarado, Camille, Chateigner-Boutin, Anne-Laure, Mortimer, Jenny,, Vigouroux, Jacqueline, Geairon, Audrey, Foucat, Loïc, Saulnier, Luc, Bouder, Axelle, Lee, Mi,, Stritt, Fabian, Scheller, Henrik,, Pauly, Markus, Falourd, Xavier, Verhertbruggen, Yves, Le Gall, Sophie   +18 more
core  

Halotolerant Bacillus sp. for Mannan Degradation Isolated from Mangrove Ecosystem at Hanura Beach Lampung

, 2020
Mannose and mannooligosaccharide acted as prebiotic that consumed by probiotic bacteria. Mannanase were the second most important enzymes for the hydrolysis of hemicelluloses, beside xylanase.
Dwi Eka Rahmawati, Christina Nugroho Ekowati, Achmad Arifiyanto, Sumardi, Salman Farisi   +4 more
core   +1 more source

Associations of CR1 polymorphism, education and occupation with high cognitive functioning in older adults: A Brazilian sample

Journal of Neuropsychology, EarlyView.
Abstract Although ageing is naturally associated with cognitive decline, some lifestyle factors, such as formal education and occupational complexity, were shown to promote the preservation of cognitive functions such as memory. Genetic factors, such as the Complement Receptor 1 (CR1) gene, were also identified to have an impact on cognition.
Gabriel Sousa Andrade, Cynthia Costa Salomão, Julia Teixeira Lucena, Patrícia de Araujo‐Souza, Amer Cavalheiro Hamdan   +4 more
wiley   +1 more source

Mannan structure analysis of the fragile Saccharomyces cerevisiae mutant VY1160

, 1983
1. 1. The fragile Saccharomyces cerevisiae mutant VY1160 has a cell-wall mannan with a lower molecular weight and a higher nitrogen content than the parental S288C strain. 2. 2.
Maerkisch, Ulrich, Reuter, Gerhard, Stateva, Lubomira, Venkov, Pencho   +3 more
core   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Active gelatin-mannan film: physicochemical, antifungal and aflatoxin binding properties

, 2019
Mannoprotein (mannan) extracted from the cell wall of Saccharomyces cerevisiae is a bioactive glycoprotein that has many biological effects. In the present work, the preparation of gelatinbased blend films containing different concentrations of mannan (0,
Jawatankuasa Kerja PSM UPM 3
core