Results 101 to 110 of about 9,297 (249)
Advanced Science, Volume 12, Issue 37, October 6, 2025.Engineered antibody‐like proteins block the SARS‐CoV‐2 spike protein from binding to host receptors and suppress immune overactivation through an MBL‐based scaffold. These dual‐function proteins effectively alleviate inflammation, complement activation, and lung injury, offering a promising therapeutic strategy against severe COVID‐19 and its ...
Yizhuo Wang +7 more
wiley +1 more source
Yeast cell wall mannan structural features, biological activities, and production strategies
HeliyonMannan and outer structural yeast cell wall polysaccharides have recently garnered attention for their health defense and cosmetic applications. In addition, many studies have confirmed that yeast cell wall mannans exhibit various biological activities ...
Kwang-Rim Baek +3 more
doaj +1 more source
Mediators of Inflammation, 1998 Rheumatoid arthritis (RA) is characterized by an abnormal cellular and cytokine infiltration of inflamed joints. This study addresses a previously unrecognized interaction between neutrophilic-myeloperoxidase (MPO) and macrophages (MΦ) which could ...
Monique P. Gelderman +7 more
doaj +1 more source
The biosynthesis of mannosyl-1-phosphoryl-polyisoprenol in Micrococcus lysodeikticus and its role in mannan synthesis. [PDF]
, 1968 Malka G. Scher +2 more
openalex +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, Volume 12, Issue 37, October 6, 2025.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Frontiers in MicrobiologyBeta-mannans are insoluble plant polysaccharides with beta-1,4-linked mannose as the backbone. We used three forms of this polysaccharide, namely, pure mannan, glucomannan, and galactomannan, to enrich haloarchaea, which have the ability to utilize ...
Dimitry Y. Sorokin +5 more
doaj +1 more source
Arthritis &Rheumatology, Volume 77, Issue 10, Page 1373-1386, October 2025.Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes +14 more
wiley +1 more source
Cancer Medicine, Volume 14, Issue 19, October 2025.This study explores how antigen peptides and sugar chains affect the efficacy of glyco‐nanovaccines (iGN) in cancer immunotherapy. We show that antigen peptides, rather than sugar chains, are key to nanoparticle uptake and immune activation, with sialic acid‐modified iGN showing similar anti‐cancer efficacy to α‐mannose‐modified iGN in a mouse model ...
Narumi Harada +10 more
wiley +1 more source
European Journal of Immunology, Volume 55, Issue 10, October 2025.Th17 cells confer protection against Candida albicans infection. In patients with STAT1 gain‐of‐function (GOF) mutations and chronic mucocutaneous candidiasis (CMC), Candida‐specific Th cell responses are numerically preserved but skewed toward Th1 and Th2.
Camilla Basso +13 more
wiley +1 more source
Structural studies of mannans from Candida albicans (serotypes A and B), Candida parapsilosis, Candida stellatoidea, and Candida tropicalis [PDF]
, 1967 R. J. Yu +4 more
openalex +1 more source