Results 111 to 120 of about 27,308 (227)
Clinical and Vaccine Immunology, 2012 Immunostimulatory properties of synthetic structures mimicking the β-(1→2)-linked mannans of Candida albicans were evaluated in vitro. Contrary to earlier observations, tumor necrosis factor (TNF) production was not detected after stimulation with ...
K. Ranta +7 more
semanticscholar +1 more source
Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines
Immunology, EarlyView.This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw +10 more
wiley +1 more source
Low Allergic Sensitisation in Wheezing Children With Down Syndrome: A Case–Control Study
Journal of Intellectual Disability Research, EarlyView.ABSTRACT Background Respiratory disorders are frequent in children with Down syndrome (DS), causing prolonged hospitalisations and increased healthcare system costs. Among these, recurrent wheezing is common in these children despite indications of lower rates of allergic sensitisation and asthma.
Francylene Malheiros Macedo da Cunha Rego +6 more
wiley +1 more source
Veterinary Medicine InternationalThe development of effective adjuvant systems remains a critical challenge in veterinary vaccine design, particularly for infectious diseases causing significant economic losses in dairy cattle. This study evaluated the immunological profile induced by a
Joaquin Cicotello +13 more
doaj +1 more source
The Cell Surface, 2019 The yeast cell wall is composed of mannoproteins, β-1,3/β-1, 6-glucans and chitin. Each of these components has technological properties that are relevant for industrial and medical applications.
Marion Schiavone +5 more
doaj +1 more source
Journal of Neuropsychology, EarlyView.Abstract Although ageing is naturally associated with cognitive decline, some lifestyle factors, such as formal education and occupational complexity, were shown to promote the preservation of cognitive functions such as memory. Genetic factors, such as the Complement Receptor 1 (CR1) gene, were also identified to have an impact on cognition.
Gabriel Sousa Andrade +4 more
wiley +1 more source
The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis
Journal of Periodontal Research, EarlyView.Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis +2 more
wiley +1 more source
Ecological and genomic variation in ectomycorrhizal fungal exploration types
New Phytologist, EarlyView.Summary Ectomycorrhizal fungi (EMF) produce mycelia with variable extension and complexity, which can be classified according to soil ‘exploration types’ (ETs). ETs have received attention as one of the few mycorrhizal trait frameworks, but without an empirical classification of ET functional diversity and environmental preferences, understanding and ...
Thomas M. Mansfield +55 more
wiley +1 more source
New Phytologist, EarlyView.Hypothetical model of Paraburkholderia–EcMF–Bishop pine interactions. Summary Whether a widespread bacterial strain of Paraburkholderia can enhance the physiological responses of ectomycorrhizal fungi (EcMF) and host Bishop pine seedling growth remains unclear. We developed a ‘top‐down meets bottom‐up’ approach that harmonized data from molecular field
Louis Berrios +3 more
wiley +1 more source