Results 41 to 50 of about 203,448 (250)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

To Dash or to Dawdle: Verb-Associated Speed of Motion Influences Eye Movements during Spoken Sentence Comprehension. [PDF]

open access: yesPLoS ONE, 2013
In describing motion events verbs of manner provide information about the speed of agents or objects in those events. We used eye tracking to investigate how inferences about this verb-associated speed of motion would influence the time course of ...
Shane Lindsay   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

MOCOnet: Robust Motion Correction of Cardiovascular Magnetic Resonance T1 Mapping Using Convolutional Neural Networks

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Quantitative cardiovascular magnetic resonance (CMR) T1 mapping has shown promise for advanced tissue characterisation in routine clinical practise.
Ricardo A. Gonzales   +10 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

MINDING YOUR MANNERS: LINGUISTIC RELATIVITY IN MOTION [PDF]

open access: yesLinguagem em (Dis)curso, 2016
Abstract Do speakers think about the world differently depending on the language they speak? In recent years, this question has generated substantial interest in the cognitive sciences, driven in part by Talmy's (1985; 2000) observations regarding the typology of motion descriptions.
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Motion Event Similarity Judgments in One or Two Languages: An Exploration of Monolingual Speakers of English and Chinese vs. L2 Learners of English

open access: yesFrontiers in Psychology, 2017
Languages differ systematically in how to encode a motion event. English characteristically expresses manner in verb root and path in verb particle; in Chinese, varied aspects of motion, such as manner, path and cause, can be simultaneously encoded in a ...
Yinglin Ji
doaj   +1 more source

The Lexicalization Patterns of Manner Motion Events in Vietnamese

open access: yesEnglish Linguistics Research, 2018
The purpose of this paper is to illustrate how Vietnamese students lexicalize or express in words the idea of motion.  This study was conducted on the traditional foundation of Talmy’s (1985) lexicalization patterns. This theory involved in the way of people’s experience is rendered into languages via the semantic content of lexical items to express ...
Luu Quy Khuong, Ly Ngoc Toan
openaire   +2 more sources

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