Results 61 to 70 of about 203,448 (250)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Acta Linguistica HafniensiaThis article aims at contributing to the theoretical tools and metalanguage used for comparing how motion, and, specifically, the enterprise of moving from one place (Loc1) to another (Loc2), is expressed across different languages. The point of departure is the well-established typological distinction between manner (or satellite-framed) languages and
openaire +1 more source
The expression of the manner of motion in Portuguese and other languages
Journal of Speech SciencesWe compared verbs expressing the manner of motion in oral narratives by speakers of Romance and Germanic languages, respectively classified as verb-framed and satellite-framed according to L. Talmy’s Motion Typology. We used a Bayesian statistical analysis on aggregated and disaggregated data from 12 speakers per language.
Aparecida Oliveira +2 more
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
How Birds Fly Differently Across Languages?—Manner Salience of Events in English and Chinese
SAGE OpenThe portrayal of motion events across languages has been extensively explored, typically focusing on human locomotion. This study, however, diverges from the norm by examining the representation of motion events associated with avian species.
Jiang Shuzhen
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Moving places. The syntax of goal of motion constructions revisited
Bucharest Working Papers in Linguistics, 2007 ‘Goal of motion’ constructions have been used in the literature (Talmy 1985, Klipple 1997, Higginbotham 1999, Rappaport Hovav and Levin 2001, Ramchand and Folli 2001, etc.) as the basis for setting a parameter which distinguishes English (a satellite ...
Ruxandra Drăgan
doaj
Frontiers in Psychology, 2019 This study tests whether Chinese learners of English can reconstruct their cognitive pattern in the direction of the target system when judging the similarity between spontaneous motion screens in a match–to–sample task.
Yinglin Ji
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Conceptualization of the Persian simple verbs of motion: a Cognitive Approach [PDF]
مطالعات زبانها و گویشهای غرب ایران, 2014 This thesis considers the conceptualization of simple motion events in Persian language from the cognitive perspective. To this end, the research data are analyzed with a Talmy's theory on frequency of occurrence of motion components in simple Persian ...
Arsalan Golfam +2 more
doaj