Results 71 to 80 of about 203,448 (250)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Metaphorical motion in modern Arabic fiction (1970–2022): analyzing the use of motion verbs and manner

open access: yesCognitive Linguistics
This study investigates metaphorical motion in modern Arabic fiction (1970–2022) to understand how motion verbs are selected and realized in abstract conceptual domains.
Othman Waleed
doaj   +1 more source

Marcher comme une reine/ Nager comme une sirène. Les verbes de déplacement et les compléments de manière en comme [PDF]

open access: yesStudii de Lingvistica, 2011
The aim of this paper is to explore the relation between lexical and syntactic encoding of manner in French by studying the combinatory potential of a small set of manner of motion verbs with comparative comme ‘as’ clauses (e.g.
Estelle Moline, Dejan Stosic
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Beyond “Move” and “Go”: A Hierarchy-Based Analysis of Chinese EFL Learners’ Acquisition of Motion Verbs

open access: yesLanguages
This study investigates how Chinese learners of English express manners of motion, examining systematic features, cognitive motivations, and compensatory strategies.
Haiyan Zhu
doaj   +1 more source

Motion into and out of in English, French and Norwegian

open access: yesNJES: Nordic Journal of English studies, 2015
This paper presents a contrastive study of Norwegian predications of motion events with the compound prepositions ut av (‘out of’) and inn i (‘into’) and their translations into English and French.
Thomas Egan, Anne-Line  Graedler
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Motion Conceptualization and Translation Difficulties (Based on English and Romanian)

open access: yesLimbaj si Context, 2015
The article examines the strategies applied in the translation of motion events from English into Romanian, taking into account the typological differences between these two languages, in Talmy’s terms, that is English expresses the manner of motion in ...
Olesea Bodean-Vozian
doaj   +1 more source

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