Results 71 to 80 of about 61,569 (245)

Localizable Fluorescent Metal Ion Indicators With Tunable Colors

Advanced Science, EarlyView.
A modular platform enables the generation of fluorescent metal ion indicators with tunable emission colors and precise subcellular localization. Conjugation to self‐labeling proteins yields bright, color‐tunable potassium probes that permit wash‐free live‐cell imaging, revealing dynamic potassium efflux in stimulated neurons.
Ming‐Ming Wang, De‐en Sun, Klara Gries, Kai Johnsson   +3 more
wiley   +1 more source

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

Non-Null Weakened Mannheim Curves in Minkowski 3-Space

Annals of the Alexandru Ioan Cuza University - Mathematics, 2015
Abstract In this study, non-null Frenet-Mannheim curves and non-null Weakened Mannheim curves are investigated in Minkowski 3-space. Some characterizations for this curves are obtained.
Tunçer, Yılmaz, Karacan, Murat Kemal, Yoon D.W.   +2 more
openaire   +2 more sources

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Community intermediary strategies and tactics to close digital divides and enhance equitable technology use in everyday life

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Online technologies are required for accessing essential services, such as healthcare, transportation, and education. Challenges to online technology access can prevent resource‐constrained communities from connecting to these services. Human intermediaries who act in the middle space between technology and the person using the technology may ...
Marcy G. Antonio, Alicia Stone, Tawanna Dillahunt, Lorraine Buis, Tiffany C. Veinot   +4 more
wiley   +1 more source

Do the Generational Cohorts of CEOs Influence Corporate Travel Emissions?

Business Strategy and the Environment, EarlyView.
ABSTRACT According to Mannheim's generational theory, each generation exhibits unique attitudes that shape its behaviour. This paper suggests that a CEO's generational background can shape their environmental views, which, in turn, influence the company's business travel policies.
Gbenga Adamolekun, Frank Kwabi, Neelu Seetaram   +2 more
wiley   +1 more source

Some Special Curves and Mannheim Curves in Three Dimensional Euclidean Space

Mathematical Sciences and Applications E-Notes, 2017
In this study we investigate some special curves which have Mannheim curves and Mannheim partnercurves and obtain some characterizations about them.
KAYMAZ, Funda, AKSOYAK, Ferdağ Kahraman
openaire   +3 more sources

Procedural Outcome of Modern Percutaneous Coronary Intervention in Proximal Chronic Total Occlusions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Long‐term outcome in patients with chronic total occlusions (CTO) depends on the target vessel and proximity of the lesion. Aims To investigate of the target vessel was associated with procedural efficacy and safety in patients with proximal CTO lesions.
Emil N. Holck, Guiseppe Vadalá, Mohamed Ayoub, Sevket Gorgulu, Alexandre Avran, Gerald S. Werner, Kambis Mashayekhi, Nihat Kalay, Omer Goktekin, Jaroslaw Wojcik, Myron Zaczkiewicz, Roberto Garbo, Juergen Arenz, Jörg Dalibor, Bas Schölzel, Nicolas Boudou, Michael Behnes, Pierfrancesco Agostoni, Carlo Di Mario, Roberto Diletti, Juan Luis Guitiérrez‐Chico, Evald H. Christiansen   +21 more
wiley   +1 more source

Statistical Strong Lensing as a Test of Conformal Gravity

Universe
As an alternative gravitational theory to General Relativity (GR), Conformal Gravity (CG) can be verified through astronomical observations. Currently, Mannheim and Kazanas have provided vacuum solutions for cosmological and local gravitational systems ...
Li-Xue Yue, Da-Ming Chen
doaj   +1 more source