Results 81 to 90 of about 208,897 (295)

Targeting Mannitol Metabolism as an Alternative Antimicrobial Strategy Based on the Structure-Function Study of Mannitol-1-Phosphate Dehydrogenase in Staphylococcus aureus [PDF]

, 2019
Mannitol-1-phosphate dehydrogenase (M1PDH) is a key enzyme in Staphylococcus aureus mannitol metabolism, but its roles in pathophysiological settings have not been established.
Bae, Taeok, Chaurasia, Akhilesh Kumar, Choi, Jongkeun, Kim, Kyeong Kyu, Kim, Truc, Lee, Seung Seo, Mizar, Pushpak, Nguyen, Thanh, Ta, Hai Minh, Yeo, Won Sik   +9 more
core   +1 more source

Evaluating Isochoric Freezing as a Strategy for Storage of Red Blood Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Red blood cells (RBCs) are needed for life‐saving blood transfusions, but they undergo continuous degradation during storage. Preserving RBCs for clinical transfusion remains a challenge due to storage‐induced damage and limitations of traditional freezing methods.
Yuanheng Zhao, Kaitlyn Wingnean, Nishaka William, Jason P. Acker   +3 more
wiley   +1 more source

Breaking the Blood–Brain Barrier with Mannitol to Aid Stem Cell Therapeutics in the Chronic Stroke Brain

Cell Transplantation, 2016
Blood–brain barrier (BBB) permeabilizers, such as mannitol, can facilitate peripherally delivered stem cells to exert therapeutic benefits on the stroke brain.
Naoki Tajiri, Jea Young Lee, Sandra Acosta, Paul R. Sanberg, Cesar V. Borlongan   +4 more
doaj   +1 more source

A comparative study on the efficacy of 10% hypertonic saline and equal volume of 20% mannitol in the treatment of experimentally induced cerebral edema in adult rats

BMC Neuroscience, 2010
Background Hypertonic saline and mannitol are commonly used in the treatment of cerebral edema and elevated intracranial pressure (ICP) at present. In this connection, 10% hypertonic saline (HS) alleviates cerebral edema more effectively than the equal ...
Fang Ming, Jiang Wen-Qiang, Deng Yi-Yu, Wang Qiao-Sheng, Zeng Hong-Ke, Chen Chun-Bo, Jiang Xin   +6 more
doaj   +1 more source

Effect of Different Direct Compaction Grades of Mannitol on the Storage Stability of Tablet Properties Investigated Using a Kohonen Self-Organizing Map and Elastic Net Regression Model

Pharmaceutics, 2020
This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability of the resulting tablets.
Atsushi Kosugi, Kok Hoong Leong, Eri Urata, Yoshihiro Hayashi, Shungo Kumada, Kotaro Okada, Yoshinori Onuki   +6 more
doaj   +1 more source

Mannitol transport and mannitol dehydrogenase activities are coordinated in olea europaea under salt and osmotic stresses [PDF]

, 2011
This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Plant and Cell Physiology following peer review. The definitive publisher-authenticated version is available online at http://pcp.oxfordjournals.org/cgi/content ...
A. Agasse, A. Conde, Angelopoulos, Blackburn, Bradford, C. Conde, Cataldi, Cheng, Cheng, Conde, Conde, Conde, Davis, DROSSOPOULOS, Ehness, Everard, Everard, Everard, Graham, H. Geros, Hernandez, Jennings, Jones, Munns, Noiraud, Oliveira, P. Silva, Prata, Rathinasabapathi, Riou-Khamlichi, Shen, Shen, Shen, Stoop, Stoop, Stoop, Tarczynski, Williamson, WINICOV, Yamamoto, Yancey, Zamski, Zamski   +42 more
core   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Effects of composition of mannitol salt agar on identification of Staphylococcus aureus

Zhongguo shipin weisheng zazhi
ObjectiveTo explore the effects of sodium chloride and tryptone in the components of mannitol salt agar on the quality of mannitol salt agar， and investigate the product quality of 5 domestic brands and 1 imported brand of mannitol salt agar sold on the ...
MA Jiaqi, LI Yanyan, LIU Xiaoyan, BAI Jichao, LIU Feng, CUI Shenghui, ZHAO Linna, YANG Baowei   +7 more
doaj   +1 more source

Role of mannitol metabolism in the pathogenicity of the necrotrophic fungus Alternaria brassicicola

Frontiers in Plant Science, 2013
In this study, the physiological functions of fungal mannitol metabolism in the pathogenicity and protection against environmental stresses were investigated in the necrotrophic fungus Alternaria brassicicola.
Benoit eCalmes, Benoit eCalmes, Benoit eCalmes, Thomas eGuillemette, Thomas eGuillemette, Thomas eGuillemette, Lény eTeyssier, Lény eTeyssier, Lény eTeyssier, Benjamin eSiegler, Sandrine ePigné, Sandrine ePigné, Sandrine ePigné, Anne eLandreau, Beatrice eIacomi, Pascal eRichomme, Rémi eLemoine, Philippe eSimoneau, Philippe eSimoneau, Philippe eSimoneau   +19 more
doaj   +1 more source