Mannose-Binding Lectin (MBL) in Health and Disease
Mannose-binding lectin (MBL) is the most intensively studied human collectin. It is recognized to be a versatile macro-molecule with many of the functional characteristics of IgM, IgG and Clq. In the presence of calcium the protein can bind to a wide spectrum of oligosaccharides through multiple lectin domains.
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Serum lectins in vertebrates play crucial roles in innate immunity as recognition molecules for pathogen-associated molecular patterns (PAMPs). In mammals, two major lectins, mannose-binding lectin (MBL) and ficolin, both containing N-terminal collagen ...
Michiyo Kimura +3 more
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Mannose-binding lectin (MBL) levels in children with Hashimoto's thyroiditis. [PDF]
Gul A, Hatipoglu N, Yilmaz R, Ates HO.
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Mannose-binding lectin gene polymorphism in psoriasis and vitiligo: an observational study and computational analysis. [PDF]
Behairy MY +7 more
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Mannose-Binding Lectin 2 as a Potential Therapeutic Target for Hepatocellular Carcinoma: Multi-Omics Analysis and Experimental Validation. [PDF]
Liao H +8 more
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Association between mannose binding lectin gene polymorphisms and clinical severity of COVID-19 in children. [PDF]
Yilmaz D +9 more
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Association of the Mannose-Binding Lectin 2 BB Genotype with COVID-19-Related Mortality. [PDF]
Kashiwagi Y +5 more
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Mannose-binding lectin suppresses macrophage proliferation through TGF-β1 signaling pathway in Nile tilapia. [PDF]
Mu L +7 more
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The association between mannose binding lectin gene polymorphisms and the risk of neonatal sepsis: an updated meta-analysis. [PDF]
Ma J +7 more
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Association of mannose-binding lectin 2 gene polymorphisms with Guillain-Barré syndrome. [PDF]
Jahan I +8 more
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