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Mannose‐binding lectin: biology and clinical implications

Internal Medicine Journal, 2005
Abstract The innate host defence molecule mannose‐binding lectin (MBL) has attracted great interest as a potential candidate for passive immunotherapy to prevent infection. MBL is a multimeric lectin that recognizes a wide array of pathogens independently of specific antibody, and initiates the lectin pathway of complement activation.
D L, Worthley   +2 more
openaire   +2 more sources

Mannose-Binding Lectin Genes

2008
Abstract Mannose-binding lectin (MBL) is an important component of the innate immune system. MBL belongs to the family of proteins called collectins, which contain both collagen-like domains and C-type lectin domains. The human collectin family includes MBL and lung surfactant proteins A and D (Holmskov et al., 1994; Lu, 1997; Lu et al.,
openaire   +1 more source

Mannose-binding lectin genetics: from A to Z

Biochemical Society Transactions, 2008
MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein. It binds sugar structures on micro-organisms and on dying host cells and is one of the four known mediators that initiate activation of the complement system via the lectin pathway.
openaire   +3 more sources

The role of mannose-binding lectin in health and disease

Molecular Immunology, 2003
Mannose-binding lectin (MBL) is a pattern recognition molecule of the innate immune system. It belongs to the collectin family of proteins in which lectin (carbohydrate-recognition) domains are found in association with collagenous structures. In man, these proteins include serum MBL, lung surfactant protein A (SP-A) and lung surfactant protein D (SP-D)
openaire   +2 more sources

Mannose-binding lectin

2000
Peter Lawson, K.B.M. Reid
openaire   +1 more source

Mannose-Binding Lectin

2018
Maciej Cedzyński   +2 more
openaire   +1 more source

Mannose-binding lectin and mannose-binding lectin–associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults

Journal of Allergy and Clinical Immunology, 2008
CARLOS Rodriguez-Gallego   +2 more
exaly  

Characterization of a mannose-binding lectin from channel catfish (Ictalurus punctatus)

Research in Veterinary Science, 2012
Liqiao Chen   +2 more
exaly  

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