Results 111 to 120 of about 61,632 (321)

Altered N-Linked Glycosylation in Follicular Lymphoma and Chronic Lymphocytic Leukemia: Involvement in Pathogenesis and Potential Therapeutic Targeting

Frontiers in Immunology, 2017
B-cell antigen receptor (BCR) expression is indispensable for survival of most B-cell malignancies. In follicular lymphoma (FL), N-linked glycosylation sites are introduced in the immunoglobulin (Ig) variable region genes.
Nurit Hollander, Joseph Haimovich
doaj   +1 more source

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

Mass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

STUDI HISTOKIMIA LEKTIN PADA SEL-SEL SPERMATOGENIK TESTIS MUNCAK (Muntiacus muntjak muntjak) (Lectin Histochemical Study of Testicular Spermatogenic Cells in Muntjak (Muntiacus muntjak muntjak))

Jurnal Kedokteran Hewan, 2016
The objective of this study was to identify the type of specific glycoconjugates and its distribution in testicular spermatogenic cells in muntjak (Muntiacus muntjak muntjak) based on lectins histochemistry.
Sri Wahyuni, Srihadi Agungpriyono, I. Ketut Mudite Adnyane, Hamny Hamny, Muhammad Jalaluddin, Gholib Gholib, Muslim Akmal, Mulyadi Adam, Dwinna Aliza, Tongku Nizwan Siregar   +9 more
doaj   +1 more source

The Role of the Mannose-Binding Lectin in Innate Immunity [PDF]

Clinical Infectious Diseases, 2005
The innate immune system, which includes mannose-binding lectin (MBL), recognizes a broad range of molecular patterns on a broad range of infectious agents and is able to distinguish them from self. MBL is a liver-derived serum protein and is secreted into the serum, where it can activate an immune response before the induction of antigen-specific ...
Kazue Takahashi, R. Alan B. Ezekowitz
openaire   +3 more sources

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: a lectin microarray-based study

BMC Cancer, 2020
Background Altered glycosylation associated with hepatocellular carcinoma (HCC) is well documented. However, few reports have investigated the association between dedifferentiation and glycosylation.
Hiroomi Takayama, Masayuki Ohta, Yukio Iwashita, Hiroki Uchida, Yuki Shitomi, Kazuhiro Yada, Masafumi Inomata   +6 more
doaj   +1 more source

Glycans from Fasciola hepatica modulate the host immune response and TLR-Induced maturation of dendritic cells [PDF]

, 2015
Helminths express various carbohydrate-containing glycoconjugates on their surface, and they release glycan-rich excretion/secretion products that can be very important in their life cycles, infection and pathology. Recent evidence suggests that parasite
Brossard, Natalie, Carmona, Carlos, Cervi, Laura Alejandra, Chiale, Carolina, Chiribao, Maria Laura, Freire, Teresa, Giacomini, Cecilia, Noya, Verónica, Rodriguez, Ernesto   +8 more
core   +3 more sources

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Clinical and pathological aspects and cerebellar lectin binding in cattle poisoned with Solanum fastigiatum var. fastigiatum and Solanum bonariense [PDF]

, 2011
Microscopic and lectin histochemical studies were performed using the cerebella of 33 natural cases of Solanum fastigiatum var. fastigiatum intoxication in the cattle from southern Brazil and 2 natural and 4 experimental cases of Solanum bonariense from ...
Barbeito, Claudio Gustavo, Barros, Claudio S.L., Gimeno, Eduardo Juan, Moraña, Antonio, Nishida, Fabian, Sant’Ana, Fabiano J.F., Verdes, José M.   +6 more
core  

Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.

, 2008
The role of Toll-like receptors (TLR) and MyD88 for immune responses to Mycobacterium tuberculosis (Mtb) infection remains controversial. To address the impact of TLR-mediated pathogen recognition and MyD88-dependent signaling events on anti ...
Abel, Bafica, Blander, Branger, Brightbill, Carroll, Cooper, Drennan, Feng, Flynn, Flynn, Fremond, Fremond, Gilleron, Gutierrez, Han, Holscher, Holscher, Hsieh, Jones, Kamath, Kaufmann, Kaufmann, Kawai, Krieg, MacMicking, MacMicking, Maher, Martinon, Means, Means, Means, Medzhitov, North, Quesniaux, Rausch, Reiling, Ryffel, Scanga, Scanga, Schaible, Seki, Shi, Shi, Shim, Sugawara, Sugawara, Sun, Takeuchi, Thoma-Uszynski, Trinchieri, Underhill, van der Wel, Yates   +53 more
core   +1 more source