Results 121 to 130 of about 15,589 (264)

Advances in Synchrotron Radiation‐Based Vacuum‐Ultraviolet Circular Dichroism for Biomolecular Structural Analysis

open access: yesChemistry – An Asian Journal, Volume 21, Issue 2, 28 January 2026.
Vacuum‐ultraviolet circular dichroism spectroscopy using synchrotron radiation is operated at the Research Institute for Synchrotron Radiation Science (HiSOR), Hiroshima University. By combining the circular dichroism technique with bioinformatics, molecular dynamics, and linear dichroism, the spectral analysis methods have been advanced, enabling ...
Koichi Matsuo   +3 more
wiley   +1 more source

Proteomic and Ubiquitinated Proteome Insights Into ER Stress Responses in Chinese Hamster Ovary Cells Under Mild Hypothermic Conditions

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 1, Page 5-25, January 2026.
Proteomic analysis of CHO cells under mild hypothermia (31°C) reveals ER stress responses, ubiquitination dynamics, and adaptive mechanisms. Magnetic immuno‐affinity enrichment and mass spectrometry highlight protein regulation differences in non‐producer versus producer cells, offering insights for optimising biopharmaceutical production of IgG1 and ...
David Ryan   +5 more
wiley   +1 more source

A single-pass type I membrane protein, mannose-specific L-type lectin, potentially involved in the adhesion and invasion of Cryptosporidium parvum

open access: yesParasite
Cryptosporidium is a globally distributed zoonotic protozoan parasite that can cause severe diarrhea in humans and animals. L-type lectins are carbohydrate-binding proteins involved in multiple pathways in animals and plants, including protein ...
Zhang Xiaotian   +9 more
doaj   +1 more source

Rice Blast Pathogenesis and Resistance: Effector Strategies and Host Defense Mechanisms

open access: yesFood and Energy Security, Volume 15, Issue 1, January/February 2026.
ABSTRACT Rice blast is the most significant disease affecting rice production, causing substantial yield loss and quality degradation. Previous studies have focused primarily on the genetic basis of pathogen resistance in rice. Recent studies have revealed the immune response mechanisms induced by pathogen‐associated molecular patterns in the pathogen ...
Lu Gan   +9 more
wiley   +1 more source

From Molecule to Meaning: Neuronopathic Biomarkers and Clinical Relevance in GM1

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT GM1 gangliosidosis is a rare, progressively neurodegenerative lysosomal storage disorder characterized by profound central nervous system involvement and substantial clinical heterogeneity. The development of reliable biomarkers is essential for tracking disease progression, stratifying patients, and advancing clinical trial readiness. Primary
Krista Casazza   +3 more
wiley   +1 more source

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