Results 121 to 130 of about 63,187 (317)
What contributes to an effective mannose recognition domain? [PDF]
, 2017 In general, carbohydrate-lectin interactions are characterized by high specificity but also low affinity. The main reason for the low affinities are desolvation costs, due to the numerous hydroxy groups present on the ligand, together with the typically ...
Eriş, Deniz +4 more
core +3 more sources
Small Structures, EarlyView.Galectin‐10 crystals prepared by cell‐free protein crystallization serve as the scaffold to capture the saccharides to determine the atomic‐resolution structure of a trisaccharide bound to protein. Molecular dynamics simulation combined with the mutation of scaffold crystals offers insights into how the binding site architecture modulates saccharide ...
Mariko Kojima +7 more
wiley +1 more source
Marine Biotechnology, 2015 We previously reported that a high-mannose binding lectin KAA-2 from the red alga Kappaphycus alvarezii, which is an economically important species and widely cultivated as a source of carrageenans, had a potent anti-influenza virus activity.
M. Hirayama +4 more
semanticscholar +1 more source
Nictaba homologs from Arabidopsis thaliana are involved in plant stress responses [PDF]
, 2018 Plants are constantly exposed to a wide range of environmental stresses, but evolved complicated adaptive and defense mechanisms which allow them to survive in unfavorable conditions.
Eggermont, Lore +2 more
core +3 more sources
Status quo and future developments in the diagnosis and treatment of hereditary angioedema
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Hereditary angioedema (HAE) is a rare hereditary disease characterized by edema, which can be life‐threatening in case of swelling in the larynx. The most common form of HAE is caused by a mutation of the SERPING1 gene and is characterized by a deficiency (type I) or loss of function (type II) of the C1 inhibitor (C1‐INH), leading to excessive ...
Andreas Recke
wiley +1 more source
The Scientific World Journal, 2014 Leishmaniasis is a vector-borne disease transmitted by phlebotomine sand fly. Susceptibility and refractoriness to Leishmania depend on the outcome of multiple interactions that take place within the sand fly gut.
Juliana Montezuma Barbosa Monteiro Tínel +13 more
doaj +1 more source
Studying Lactoferrin N-Glycosylation. [PDF]
, 2017 Lactoferrin is a multifunctional glycoprotein found in the milk of most mammals. In addition to its well-known role of binding iron, lactoferrin carries many important biological functions, including the promotion of cell proliferation and ...
Barile, Daniela +4 more
core +3 more sources
Blood group O expression in normal tissues and tumors
The FEBS Journal, EarlyView.The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. Two novel monoclonal antibodies generated using sea lamprey immunization, Tn4‐31L and OmcFL3‐02, specifically detect the H antigen on glycan microarrays, glycoproteins, and human cells.
Ea Kristine Clarisse Tulin +11 more
wiley +1 more source
The FEBS Journal, EarlyView.Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
Screening and partial characterization of lectins from Indonesian seaweeds
Applied PhycologyLectins are carbohydrate-binding proteins involved in diverse biological processes with potential biotechnological and biomedical applications. Seaweeds are promising sources of novel lectins with unique structures and glycan specificities.
Nurrahmi D Fajarningsih +4 more
doaj +1 more source