Results 131 to 140 of about 63,187 (317)

Mannose-Binding Lectin Binds to Amyloid β Protein and Modulates Inflammation

open access: yesJournal of Biomedicine and Biotechnology, 2012
Mannose-binding lectin (MBL), a soluble factor of the innate immune system, is a pattern recognition molecule with a number of known ligands, including viruses, bacteria, and molecules from abnormal self tissues.
M. Larvie   +8 more
semanticscholar   +1 more source

Toxins for Transgenic Resistance to Hemipteran Pests [PDF]

open access: yes, 2012
The sap sucking insects (Hemiptera), which include aphids, whiteflies, plant bugs and stink bugs, have emerged as major agricultural pests. The Hemiptera cause direct damage by feeding on crops, and in some cases indirect damage by transmission of plant ...
Bonning, Bryony   +2 more
core   +3 more sources

Role of the Mannose‐Binding Lectin in Innate Immunity [PDF]

open access: yesThe Journal of Infectious Diseases, 2003
The ability to recognize infectious agents from self is intrinsic to innate immunity. One basic tenet of innate immunity is the evolution of classes of molecules that are termed "pattern-recognition" receptors and molecules. Many pattern-recognition molecules conspire together to protect the host in the first minutes and hours after exposure to an ...
openaire   +3 more sources

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

open access: yesThe FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher   +7 more
wiley   +1 more source

Memory in the wall: expanding our understanding of the roles of plant cell walls

open access: yesNew Phytologist, EarlyView.
Summary The plant cell wall, while providing mechanical support to cells, also dynamically adjusts its composition and structure in response to cellular and environmental cues. Recent findings indicate that plants exposed to cold stress alter the composition of cell wall polysaccharides and that this altered status primes the plants to overcome future,
Hiromasa Shikata   +3 more
wiley   +1 more source

Synthesis and optimization of octavalent bolaamphiphile preparation with terminal D-mannose residues

open access: yesТонкие химические технологии, 2015
In this article a scheme was proposed, and the synthesis of octavalent bolaamphiphile with terminal D-mannose residues was carried out. The technique of the laboratory synthesis of this compound was improved using optimisation of the key step of the ...
V. B. Gostenin   +2 more
doaj  

The Pepper Mannose-Binding Lectin Gene CaMBL1 Is Required to Regulate Cell Death and Defense Responses to Microbial Pathogens1[C][W][OA]

open access: yesPlant Physiology, 2011
Plant mannose-binding lectins (MBLs) are crucial for plant defense signaling during pathogen attack by recognizing specific carbohydrates on pathogen surfaces. In this study, we isolated and functionally characterized a novel pepper (Capsicum annuum) MBL
I. Hwang, B. Hwang
semanticscholar   +1 more source

Glycosylation in the thyroid gland : vital aspects of glycoprotein function in thyrocyte physiology and thyroid disorders [PDF]

open access: yes, 2018
The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins.
Ewa Pocheć   +2 more
core   +1 more source

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer   +2 more
wiley   +1 more source

High Mannose-binding Lectin with Preference for the Cluster of α1–2-Mannose from the Green Alga Boodlea coacta Is a Potent Entry Inhibitor of HIV-1 and Influenza Viruses*

open access: yesJournal of Biological Chemistry, 2011
The complete amino acid sequence of a lectin from the green alga Boodlea coacta (BCA), which was determined by a combination of Edman degradation of its peptide fragments and cDNA cloning, revealed the following: 1) B.
Yuichiro Sato   +5 more
semanticscholar   +1 more source

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