The Role of Macrophages in Cancer: From Basic Research to Clinical Applications
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu +5 more
wiley +1 more source
Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz +5 more
wiley +1 more source
From Sea to Sweet: Seaweed's Role in Nutritious and Sustainable Confectionery
ABSTRACT Seaweed is increasingly recognized as a multifunctional ingredient in confectionery products, owing to its exceptional nutritional profile, functional properties, and environmental sustainability. This review highlights the integration of seaweed and seaweed‐derived compounds into a wide range of confectioneries, including chocolates, puddings,
Nima Mohammadi, Nikoo Ostovar
wiley +1 more source
A combination of the HLA-DRB1*03 phenotype and low plasma mannose-binding lectin predisposes to autoantibody formation in women with recurrent pregnancy loss [PDF]
Caroline Nørgaard-Pedersen +3 more
openalex +1 more source
Memory in the wall: expanding our understanding of the roles of plant cell walls
Summary The plant cell wall, while providing mechanical support to cells, also dynamically adjusts its composition and structure in response to cellular and environmental cues. Recent findings indicate that plants exposed to cold stress alter the composition of cell wall polysaccharides and that this altered status primes the plants to overcome future,
Hiromasa Shikata +3 more
wiley +1 more source
Polymorphisms in Genes Coding for Cytokines, Mannose-Binding Lectin, Collagen Metabolism and Thrombophilia in Women with Cervical Insufficiency [PDF]
Iben Sundtoft +4 more
openalex +1 more source
Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection
ABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Arieli Bernardo Portugal +3 more
wiley +1 more source
Mannose binding lectin genotypes are not associated with increased risk of unexplained recurrent pregnancy loss [PDF]
Dara S. Berger +3 more
openalex +1 more source
Comprehensive glycomics analysis and genome‐wide DNA methylation analysis using tissue samples of clear cell renal cell carcinoma (ccRCC) have revealed that the glycan profile, including “immature” N‐type glycans, may be attributable to epigenetic regulation of glycogenes.
Yoshiko Kitazume +11 more
wiley +1 more source

