Results 21 to 30 of about 15,589 (264)

Mannose-Binding Lectin in HIV Infection [PDF]

open access: yesFuture Virology, 2008
Infection with HIV represents a significant global health problem, with high infection rates and high mortality worldwide. Treatment with antiretroviral therapy is inaccessible to many patients and efficacy is limited by development of resistance and side effects.
Sarah, Eisen   +2 more
openaire   +2 more sources

Structural determinants for activity and specificity of the bacterial toxin LlpA. [PDF]

open access: yesPLoS Pathogens, 2013
Lectin-like bacteriotoxic proteins, identified in several plant-associated bacteria, are able to selectively kill closely related species, including several phytopathogens, such as Pseudomonas syringae and Xanthomonas species, but so far their mode of ...
Maarten G K Ghequire   +5 more
doaj   +1 more source

BanLec-eGFP Chimera as a Tool for Evaluation of Lectin Binding to High-Mannose Glycans on Microorganisms

open access: yesBiomolecules, 2021
Fluorescently labeled lectins are useful tools for in vivo and in vitro studies of the structure and function of tissues and various pathogens such as viruses, bacteria, and fungi.
Zorana Lopandić   +5 more
doaj   +1 more source

Legume Lectins with Different Specificities as Potential Glycan Probes for Pathogenic Enveloped Viruses

open access: yesCells, 2022
Pathogenic enveloped viruses are covered with a glycan shield that provides a dual function: the glycan structures contribute to virus protection as well as host cell recognition.
Annick Barre   +6 more
doaj   +1 more source

Retrospective screening of serum IgG glycosylation biomarker for primary Sjögren’s syndrome using lectin microarray [PDF]

open access: yesPeerJ, 2023
Background Primary Sjögren’s syndrome (PSS) is a systemic autoimmune disease resulting in significant loss of systemic gland secretory function. IgG glycosylation abnormalities had been found to play important roles in autoimmune diseases.
Siting Li   +7 more
doaj   +2 more sources

Differential effect of plant lectins on mast cells of different origins

open access: yesBrazilian Journal of Medical and Biological Research, 2005
Histamine release induced by plant lectins was studied with emphasis on the carbohydrate specificity, external calcium requirement, metal binding sites, and mast cell heterogeneity and on the importance of antibodies bound to the mast cell membrane to ...
F.C. Lopes   +4 more
doaj   +1 more source

Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model. [PDF]

open access: yesPLoS ONE, 2015
Trichomonas vaginalis causes vaginitis and increases the risk of HIV transmission by heterosexual sex, while Tritrichomonas foetus causes premature abortion in cattle. Our goals were to determine the effects, if any, of anti-retroviral lectins, which are
Aparajita Chatterjee   +8 more
doaj   +1 more source

Activity of mannose‐binding lectin in centenarians [PDF]

open access: yesAging Cell, 2012
SummaryWe analyzed MBL2 gene variants in two cohorts of centenarians, octo‐nonagenarians and nonagenarians, and in the general population, one from Sardinia Island (Italy), recruited in the frame of the AKea study, and another from Campania (southern Italy), to search for haplotypes related to longevity.
TOMAIUOLO, R   +12 more
openaire   +4 more sources

Promiscuity of the Euonymus Carbohydrate-Binding Domain

open access: yesBiomolecules, 2012
Plants synthesize small amounts of carbohydrate-binding proteins on exposure to stress. For example, on exposure to drought, high salt, wounding and by treatment with some plant hormones or by pathogen attack. In contrast to the ‘classical’ plant lectins
Els J.M. Van Damme, Elke Fouquaert
doaj   +1 more source

Microglial Lectins in Health and Neurological Diseases

open access: yesFrontiers in Molecular Neuroscience, 2018
Microglia are the innate sentinels of the central nervous system (CNS) and are responsible for the homeostasis and immune defense of the CNS. Under the influence of the local environment and cell-cell interaction, microglia exhibit a multidimensional and
Jian Jing Siew   +3 more
doaj   +1 more source

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