Results 61 to 70 of about 175,359 (294)

Effects of .ALPHA.-D-mannose and equilibrated D-mannose on insulin release.

Endocrinologia Japonica, 1978
The effects on insulin release of alpha-D-mannose and equilibrated D-mannose were studied in the isolated perfused rat pancreas. Although phosphomannose isomerase, in contrast to phosphoglucose isomerase, is stereospecific for beta-D-mannose-6-phosphate, the alpha anomer of D-mannose (2 mg/ml) was significantly more effective than equilibrated D ...
Ichitomo Miwa, Hatsumi Niki, Atsushi Niki   +2 more
openaire   +4 more sources

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Antibiotic tolerance due to restriction of cAMP-Crp regulation by mannitol, a non-glucose-family PTS carbon source

mSphere
Enzyme-IIA (EIIAGlc, Crr) of the phosphotransferase system (PTS) connects the uptake of glucose-family sugars to the cAMP-Crp regulatory cascade; phosphorylated EIIAGlc enhances cAMP-Crp activity, which then contributes to the antibiotic-mediated ...
Weiwei Zhu, Miaomiao Chen, Xue Zhang, Jie Su, Xinyang Zhang, Yuejuan Nong, Bowen Wang, Weihong Guo, Yunxin Xue, Dai Wang, Yiqun Liao, Jianjun Niu, Yuzhi Hong, Karl Drlica, Xilin Zhao   +14 more
doaj   +1 more source

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Advanced Healthcare Materials, EarlyView.
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley   +1 more source

Design, synthesis and biological evaluation of immunostimulating mannosylated desmuramyl peptides

Beilstein Journal of Organic Chemistry, 2019
Muramyl dipeptide is the minimal structure of peptidoglycan with adjuvant properties. Replacement of the N-acetylmuramyl moiety and increase of lipophilicity are important approaches in the preparation of muramyl dipeptide analogues with improved ...
Rosana Ribić, Ranko Stojković, Lidija Milković, Mariastefania Antica, Marko Cigler, Srđanka Tomić   +5 more
doaj   +1 more source

The ‘involution’ of mannose-binding lectin [PDF]

Human Molecular Genetics, 2005
Mannose-binding lectin (MBL) acts as a serum opsonin in innate immune defense and induces complement activation by the lectin pathway. In humans, low levels of functional serum MBL are caused by the dominant action of three single nucleotide substitutions in exon 1 that disrupt the glycine-rich backbone structure of the protein.
Hans O. Madsen, Peter Garred, Jeanette Seyfarth   +2 more
openaire   +3 more sources

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

Ionic Conductive Textiles for Wearable Technology

Advanced Materials, EarlyView.
Recent advances in ionic conductive textiles for wearable technology are summarized, with a focus on soft ionic conductors that exhibit skin‐like flexibility and tissue‐like ion dynamics. Their structures, key characteristics, manufacturing methods, and diverse applications are reviewed.
Lingtao Fang, Yunlu Zhou, Qiyao Huang
wiley   +1 more source

Mannose metabolism in the human erythrocyte [PDF]

Journal of Clinical Investigation, 1969
The metabolism of mannose by human erythrocytes has been investigated. Phosphorylation of mannose is achieved by an enzyme with electrophoretic mobility on starch gel indistinguishable from the glucose-phosphorylating enzyme. Mannose phosphorylation is competitively inhibited by glucose; glucose phosphorylation is competitively inhibited by mannose ...
Leslie Teeple, Ernest Beutler
openaire   +2 more sources

Gradients of Aliveness and Engineering: A Taxonomy of Fungal Engineered Living Materials

Advanced Materials, EarlyView.
This paper explores the potential of fungal engineered living materials (ELMs), examining fungal biology and growth mechanisms, which underpin their development. It presents a classification framework based on aliveness, scaffold composition, and engineering degree. Unique properties such as self‐healing, biosensing, and bioremediation are highlighted,
Elise Elsacker, Jara Saluena Martin, Annah‐Ololade Sangosanya, Anouk Verstuyft, Aurélie Van Wylick, Eveline Peeters   +5 more
wiley   +1 more source