Results 1 to 10 of about 135,703 (297)

Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]

open access: yes, 2001
The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S.   +2 more
core   +1 more source

Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.

open access: yesPLoS Pathogens, 2008
Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus ...
Sigrid E M Heinsbroek   +5 more
doaj   +1 more source

Cooperative stimulation of dendritic cells by Cryptococcus neoformans mannoproteins and CpG oligodeoxynucleotides.

open access: yesPLoS ONE, 2008
While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Jennifer M Dan   +3 more
doaj   +1 more source

Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.

open access: yes, 2008
The role of Toll-like receptors (TLR) and MyD88 for immune responses to Mycobacterium tuberculosis (Mtb) infection remains controversial. To address the impact of TLR-mediated pathogen recognition and MyD88-dependent signaling events on anti ...
Abel   +53 more
core   +1 more source

Endoplasmic Reticulum Export of GPI-Anchored Proteins [PDF]

open access: yes, 2019
Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat complex COPII, which forms vesicles at ER exit sites for transport of correctly assembled secretory cargo to the Golgi apparatus ...
López Martín, Sergio   +3 more
core   +1 more source

Mannose-functionalization of reconstituted high-density lipoprotein nanoparticles improves payload delivery and enhances M2-to-M1 phenotype reprogramming of RAW 264.7 macrophages polarized by B16-F10 melanoma cells

open access: yesFrontiers in Drug Delivery, 2023
The targeting and conversion of the immunosuppressive (M2) tumor-associated macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor regression in advanced melanoma.
Akpedje S. Dossou   +5 more
doaj   +1 more source

Mannose receptor regulates motility [PDF]

open access: yesThe Journal of Cell Biology, 2006
![Graphic][1] Myoblasts fail to fuse if they lack the mannose receptor (bottom). If myoblasts are to fuse with nascent myotubes and thus form muscles, they must apparently migrate and chew up extracellular matrix (ECM), according to Jansen and Pavlath (page [403][2 ...
openaire   +1 more source

Mannose Receptor Ligands Regulate the Gene Expression of Toll-like Receptors in Chicken Monocytes

open access: yesThe Journal of Poultry Science, 2013
Pattern recognition receptors play an important role in distinguishing foreign organisms and triggering host defense responses. In this study, we present evidence for differential immune responses in chicken monocytes exposed to the mannose receptor (MR)
Li Yan, Zandong Li
doaj   +1 more source

Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages

open access: yeseLife, 2020
HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages. Evolutionary conservation of Vpr suggests an important yet poorly understood role for macrophages in HIV pathogenesis.
Jay Lubow   +11 more
doaj   +1 more source

Experimental Trichinellosis in rats: Peritoneal macrophage activity [PDF]

open access: yesArchives of Biological Sciences, 2010
The influence of Trichinella spiralis infection on macrophage activity in rats during the first 28 days of infection was examined by measuring the production of NO and IL-6, as well as the expression of mannose receptor on the surface of peritoneal ...
Gruden-Movsesijan Alisa   +1 more
doaj   +1 more source

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