Results 1 to 10 of about 135,703 (297)
Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]
The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S. +2 more
core +1 more source
Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.
Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus ...
Sigrid E M Heinsbroek +5 more
doaj +1 more source
While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Jennifer M Dan +3 more
doaj +1 more source
The role of Toll-like receptors (TLR) and MyD88 for immune responses to Mycobacterium tuberculosis (Mtb) infection remains controversial. To address the impact of TLR-mediated pathogen recognition and MyD88-dependent signaling events on anti ...
Abel +53 more
core +1 more source
Endoplasmic Reticulum Export of GPI-Anchored Proteins [PDF]
Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat complex COPII, which forms vesicles at ER exit sites for transport of correctly assembled secretory cargo to the Golgi apparatus ...
López Martín, Sergio +3 more
core +1 more source
The targeting and conversion of the immunosuppressive (M2) tumor-associated macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor regression in advanced melanoma.
Akpedje S. Dossou +5 more
doaj +1 more source
Mannose receptor regulates motility [PDF]
![Graphic][1] Myoblasts fail to fuse if they lack the mannose receptor (bottom). If myoblasts are to fuse with nascent myotubes and thus form muscles, they must apparently migrate and chew up extracellular matrix (ECM), according to Jansen and Pavlath (page [403][2 ...
openaire +1 more source
Mannose Receptor Ligands Regulate the Gene Expression of Toll-like Receptors in Chicken Monocytes
Pattern recognition receptors play an important role in distinguishing foreign organisms and triggering host defense responses. In this study, we present evidence for differential immune responses in chicken monocytes exposed to the mannose receptor (MR)
Li Yan, Zandong Li
doaj +1 more source
Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages
HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages. Evolutionary conservation of Vpr suggests an important yet poorly understood role for macrophages in HIV pathogenesis.
Jay Lubow +11 more
doaj +1 more source
Experimental Trichinellosis in rats: Peritoneal macrophage activity [PDF]
The influence of Trichinella spiralis infection on macrophage activity in rats during the first 28 days of infection was examined by measuring the production of NO and IL-6, as well as the expression of mannose receptor on the surface of peritoneal ...
Gruden-Movsesijan Alisa +1 more
doaj +1 more source

