Results 21 to 30 of about 135,703 (297)
Molecules, 2022 Punicalagin is the most bioactive pomegranate polyphenol with high antioxidant and free-radical scavenging activity and can potentially cure different ailments related to the cardiovascular system.
Ritu Karwasra +6 more
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Revista da Sociedade Brasileira de Medicina Tropical, 2021 We describe the first report of a patient with chronic mucocutaneous candidiasis associated with disseminated and recurrent paracoccidioidomycosis. The investigation demonstrated that the patient had a mannose receptor deficiency, which would explain the
Dewton de Moraes Vasconcelos +2 more
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Mannosylation of virus-like particles enhances internalization by antigen presenting cells. [PDF]
PLoS ONE, 2014 Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptive immune response. Mannosylation has been demonstrated to enhance antigen uptake through mannose receptors, leading to improved immune responses.
Farah Al-Barwani +4 more
doaj +1 more source
Nature Communications, 2021 Red blood cells (RBCs) are phagocytosed in the spleen in sickle cell disease and malaria. Here, Cao et al. show that high mannose N-glycans, exposed on diseased or oxidized RBC surfaces, bind mannose receptor CD206 on host cells, mediating phagocytosis.
Huan Cao +27 more
doaj +1 more source
Cells, 2021 Betacoronaviruses, responsible for the “Severe Acute Respiratory Syndrome” (SARS) and the “Middle East Respiratory Syndrome” (MERS), use the spikes protruding from the virion envelope to attach and subsequently infect the host cells.
Annick Barre +7 more
doaj +1 more source
Human immunodeficiency virus-1 uses the mannose-6-phosphate receptor to cross the blood-brain barrier. [PDF]
PLoS ONE, 2012 HIV-1 circulates both as free virus and within immune cells, with the level of free virus being predictive of clinical course. Both forms of HIV-1 cross the blood-brain barrier (BBB) and much progress has been made in understanding the mechanisms by ...
Shinya Dohgu +3 more
doaj +1 more source
Cell surface-specific N-glycan profiling in breast cancer [PDF]
, 2013 Aberrant changes in specific glycans have been shown to be associated with immunosurveillance, tumorigenesis, tumor progression and metastasis. In this study, the N-glycan profiling of membrane proteins from human breast cancer cell lines and tissues was
Chen, Cuiying +8 more
core +10 more sources
Journal of Leukocyte Biology, 2012 Abstract Review on mannose receptor as an endocytic receptor in antigen delivery that is co-expressed with the microRNA miR-511-3p encoded within the Mrc1 gene. The MR is a highly effective endocytic receptor with a broad binding specificity encompassing ligands of microbial and endogenous origin and a poorly characterized
openaire +2 more sources
pH-Degradable mannosylated nanogels for dendritic cell targeting [PDF]
, 2016 We report on the design of glycosylated nanogels via core-cross linking of amphiphilic non-water-soluble block copolymers composed of an acetylated glycosylated block and a pentafluorophenyl (PFP) activated ester block prepared by reversible addition ...
Ayres, Neil +12 more
core +2 more sources
A detailed study on understanding glycopolymer library and Con A interactions [PDF]
, 2013 Synthetic glycopolymers are important natural oligosaccharides mimics for many biological applications. To develop glycopolymeric drugs and therapeutic agents, factors that control the receptor-ligand interaction need to be investigated.
Becer, C. Remzi +5 more
core +1 more source