Characterization of functional mannose receptor in a continuous hybridoma cell line
BMC Immunology, 2012 Background The mannose receptor is the best described member of the type I transmembrane C-type lectins; however much remains unanswered about the biology of the receptor.
Vigerust David J +2 more
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Signals involved in protein intracellular sorting [PDF]
, 2005 “…Confusion appears to occur just after the articulation of a major conceptual advance that served to greatly clarify a problem of exceptional importance.”- Ira Mellman, 1996.
Nair, Prashant
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"In vitro" reconstitution of "trans"-Golgi exit and the effect of GAG attachment on protein sorting [PDF]
, 2007 The trans-Golgi network is one of the main sorting stations for proteins and lipids in the eukaryotic endomembrane system. Yet, the mechanisms for sorting and transport out of the trans-Golgi network remain poorly understood.
Kobialka, Szymon
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Mannose Receptor as a Potential Biomarker for Gastric Cancer: A Pilot Study
The International Journal of Biological Markers, 2017 Background The mannose receptor is an immune adhesion molecule mainly expressed on the surface of antigen-presenting cells such as nonmature dendritic cells and macrophages.
Deng-Rui Liu +4 more
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High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus [PDF]
, 2011 Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin.
Bee K. Tan +19 more
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Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism [PDF]
, 1989 The removal of neutrophils and their histotoxic contents from the inflamed site is a prerequisite for resolution of tissue injury, and a point at which factors critical to the pathogenesis of chronic inflammation may act.
Savill, John S +5 more
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The Mannose Receptor Is Involved in the Phagocytosis of Mycobacteria-Induced Apoptotic Cells
Journal of Immunology Research, 2016 Upon Mycobacterium tuberculosis infection, macrophages may undergo apoptosis, which has been considered an innate immune response. The pathways underlying the removal of dead cells in homeostatic apoptosis have been extensively studied, but little is ...
Teresa Garcia-Aguilar +3 more
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Molecules, 2019 Macrophages play an important role in the regulation of inflammation and immune response as well as the pathogenesis of chronic inflammatory diseases and cancer.
Kai Shibaguchi +5 more
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, 2003 Lysosomes are membrane-bound organelles that serve in the degradation of many extracellular and intracellular macromolecules. Lysosomal biogenesis depends on the delivery of newly synthesized lysosomal hydrolases. This process requires the acquisition
Stöckli, Jacqueline
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Protein-carbohydrate interactions during fertilization [PDF]
, 1998 Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during
Plendl, J., Sinowatz, Fred, Kolle, S.
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