Results 31 to 40 of about 1,345,412 (243)

AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid. [PDF]

, 2007
BACKGROUND: Surfactant protein D (SP-D) and Mannose Binding Lectin (MBL) are collectins that have opsonic and immunoregulatory functions, are found in lung fluid and interact with the human immunodeficiency virus (HIV).
Ed Zijlstra, Jambo Kondwani C, Zijlstra, Ed, Jambo, Kondwani C, Gordon, Stephen, French Neil, Jambo, Kondwani, Kondwani C Jambo, Neil French, Stephen B Gordon, French, Neil, Gordon, Stephen B, Zijlstra Ed, Gordon Stephen B, Kondwani C Jambo   +14 more
core   +2 more sources

The mannose receptor mediates dengue virus infection of macrophages. [PDF]

PLoS Pathogens, 2008
Macrophages (MØ) and mononuclear phagocytes are major targets of infection by dengue virus (DV), a mosquito-borne flavivirus that can cause haemorrhagic fever in humans. To our knowledge, we show for the first time that the MØ mannose receptor (MR) binds
Joanna L Miller, Barend J M de Wet, Luisa Martinez-Pomares, Catherine M Radcliffe, Raymond A Dwek, Pauline M Rudd, Siamon Gordon   +6 more
doaj   +1 more source

Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia. [PDF]

, 2012
BACKGROUND: Mannose-binding Lectin protein (MBL) has been suggested to be relevant in the defence against infections in immunosuppressed individuals.
Öhrmalm, Lars, Michelle Wong, Ohrmalm, L, Öhrmalm L., Lars Öhrmalm, Aust Carl, Tolfvenstam, Thomas, Tolfvenstam T., Hibberd, Martin, Wong, Michelle, Martin Hibberd, Hibberd M., Broliden K., Tolfvenstam, T,, Hibberd, M, Kristina Broliden, Thomas Tolfvenstam, Broliden, K,, Broliden, Kristina, Hibberd Martin, Broliden Kristina, Aust, C,, Wong, M, Carl Aust, Aust C., Wong M., Tolfvenstam Thomas, Öhrmalm Lars, Wong Michelle, Aust, Carl   +29 more
core   +2 more sources

The Mannose Receptor in Regulation of Helminth-Mediated Host Immunity

Frontiers in Immunology, 2017
Infection with parasitic helminths affects humanity and animal welfare. Parasitic helminths have the capacity to modulate host immune responses to promote their survival in infected hosts, often for a long time leading to chronic infections.
Irma van Die, Richard D. Cummings
doaj   +1 more source

Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]

, 2010
Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M., Huitinga, I., Voehringer, David, Raes, G., van Eijk, Marco, Hoek, Robert M., Hamann, J., Huitinga, Inge, Koning, N., Brouwer, M.S., Raes, Geert, Pouwels, W., Voehringer, D., Koning, Nathalie, Van Eijk, M., Hoek, R.M., Pouwels, Walter, Hamann, Jörg   +17 more
core   +1 more source

Mannoside-Modified Branched Gold Nanoparticles for Photothermal Therapy to MDA-MB-231 Cells

Molecules, 2020
Recently, gold nanoparticles (Au NPs) have been used to study the treatment of malignant tumors due to their higher biocompatibility and lesser toxicity.
Han-Chen Lin, Keng-Fang Hsu, Chiao-Ling Lai, Tzu-Chien Wu, Hui-Fen Chen, Chian-Hui Lai   +5 more
doaj   +1 more source

Mannose-Coated Fluorescent Lipid Microparticles for Specific Cellular Targeting and Internalization via Glycoreceptor-Induced Phagocytosis

, 2019
In this work, we report on the development of mannose-coated fluorescent lipid microparticles to study the role of C-type lectin membrane receptors in phagocytosis.
Jean-Maurice Mallet (1794211), Léa Pinon (7817543), Jacques Fattaccioli (7038902), Lorraine Montel (5316863), Laurent Cattiaux (7817546), Pascal Matton (2062834), Blaise Dumat (1919137)   +6 more
core   +2 more sources

Transient Production of Human β-Glucocerebrosidase With Mannosidic-Type N-Glycan Structure in Glycoengineered Nicotiana benthamiana Plants

Frontiers in Plant Science, 2021
Gaucher disease is an inherited lysosomal storage disorder caused by a deficiency of functional enzyme β-glucocerebrosidase (GCase). Recombinant GCase has been used in enzyme replacement therapy to treat Gaucher disease. Importantly, the terminal mannose
Naphatsamon Uthailak, Hiroyuki Kajiura, Hiroyuki Kajiura, Ryo Misaki, Ryo Misaki, Kazuhito Fujiyama, Kazuhito Fujiyama, Kazuhito Fujiyama   +7 more
doaj   +1 more source

Mannose-functionalization of reconstituted high-density lipoprotein nanoparticles improves payload delivery and enhances M2-to-M1 phenotype reprogramming of RAW 264.7 macrophages polarized by B16-F10 melanoma cells

Frontiers in Drug Delivery, 2023
The targeting and conversion of the immunosuppressive (M2) tumor-associated macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor regression in advanced melanoma.
Akpedje S. Dossou, Morgan E. Mantsch, Nirupama Sabnis, Rance E. Berg, Rafal Fudala, Andras G. Lacko   +5 more
doaj   +1 more source

Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.

PLoS Pathogens, 2008
Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus ...
Sigrid E M Heinsbroek, Philip R Taylor, Fernando O Martinez, Luisa Martinez-Pomares, Gordon D Brown, Siamon Gordon   +5 more
doaj   +1 more source