Results 101 to 110 of about 224,774 (318)
Aggregate, EarlyView.Diabetic wound healing is blocked by persistent inflammation and oxidative stress. Bioactive substances like growth factors and Hsts promote repair but lack long‐term stability. Herein, a platelet membrane‐coated nanoparticle system (PNP) is proposed to achieve enhanced retention of aggregation‐induced emissive (AIE) molecular‐modified Hst1 (Hst1‐AIE ...
Xiaoxuan Lei +9 more
wiley +1 more source
Subcellular Localization of Mannose 6-Phosphate Glycoproteins in Rat Brain [PDF]
Journal of Biological Chemistry, 1999 The intracellular transport of soluble lysosomal enzymes relies on the post-translational modification of N-linked oligosaccharides to generate mannose 6-phosphate (Man 6-P) residues. In most cell types the Man 6-P signal is rapidly removed after targeting of the precursor proteins from the Golgi to lysosomes via interactions with Man 6-phosphate ...
John E. Pintar +9 more
openaire +4 more sources
Mannitol metabolism during pathogenic fungal-host interactions under stressed conditions
Frontiers in Microbiology, 2015 Numerous plants and fungi produce mannitol, which may serve as an osmolyte or metabolic store; furthermore, mannitol also acts as a powerful quencher of reactive oxygen species (ROS).
Ram Sanmukh Upadhyay +4 more
doaj +1 more source
Synthesis of Mannose‐6‐Phosphate Analogues and their Utility as Angiogenesis Regulators [PDF]
ChemMedChem, 2011 Although carbohydrates are the most abundant natural products, their use as therapeutic agents has been limited. However, since carbohydrate binding proteins are involved in many biological processes, including cellular communication, the prospects for carbohydrate-based drugs seem bright.
Barragan-Montero, Véronique +6 more
openaire +4 more sources
6R/S-deutero-α-d-mannopyranoside 1-phosphate
Molbank, 2019 6R/S-deutero-α-d-mannopyranoside 1-phosphate was synthesised from a C6 aldehydic mannose thioglycoside donor in four steps. Using NaBD4 as the reductant, isotopic enrichment at C6 was achieved and the resultant C6-deuterated material was converted ...
Sanaz Ahmadipour, Gavin J. Miller
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek +5 more
wiley +1 more source
High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300 [PDF]
, 2016 To characterize the interaction potential of the human vaginal isolate Lactobacillus plantarum CMPG5300, its genome was mined for genes encoding lectin-like proteins.
Balzarini, Jan +10 more
core +1 more source
Data for analysis of mannose-6-phosphate glycans labeled with fluorescent tags
Data in Brief, 2016 Mannose-6-phosphate (M-6-P) glycan plays an important role in lysosomal targeting of most therapeutic enzymes for treatment of lysosomal storage diseases.
Ji-Yeon Kang +3 more
doaj
PLoS ONE, 2012 Prominent vasculopathy in Fabry disease patients is caused by excessive intracellular accumulation of globotriaosylceramide (GL-3) throughout the vascular endothelial cells causing progressive cerebrovascular, cardiac and renal impairments.
T. Prabakaran +6 more
semanticscholar +1 more source
Animal Research and One Health, EarlyView.Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li +10 more
wiley +1 more source