Results 131 to 140 of about 224,774 (318)
Here, a green synthetic approach through spontaneous adsorption and laccase‐induced reactions is introduced to functionalize lignin nanoparticles (LNPs) with hemicelluloses. The resulting lignin–hemicellulose hybrid nanoparticles presented increase colloidal stability at acidic pH compared to the plain LNPs, encouraging their usage in different areas ...
Patrícia Figueiredo+4 more
wiley +1 more source
Subpopulations of liver coated vesicles resolved by preparative agarose gel electrophoresis. [PDF]
Rat liver clathrin coated vesicles (CVs) were separated into several distinct subpopulations using non-sieving concentrations of agarose, which allowed the separation of species differing primarily in surface charge.
Hill, DF+3 more
core
Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation
Niemann-Pick disease type C (NPC), caused by mutations in the NPC1 gene or the NPC2 gene, is characterized by the accumulation of unesterified cholesterol and other lipids in endo/lysosomal compartments.
Marion Willenborg+6 more
doaj
The endosomal concentration of a mannose 6-phosphate receptor is unchanged in the absence of ligand synthesis. [PDF]
Suzanne R. Pfeffer
openalex +1 more source
Analysis of Mannose 6-Phosphate Uncovering Enzyme Mutations Associated with Persistent Stuttering*
Background: Three mutations in the NAGPA gene encoding uncovering enzyme (UCE) have been found in some individuals with persistent stuttering. Results: All three mutations lead to lower UCE activity.
Wang-Sik Lee+3 more
semanticscholar +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The cation-independent mannose 6-phosphate receptors (CI-M6PR) bind newly synthesized mannose 6-phosphate (Man-6-P)-tagged enzymes in the Golgi and transport them to late endosomes/lysosomes, providing them with degradative functions.
Shalini Rawat, Mahak Sharma
doaj +1 more source
Isolation and characterization of membranes from bovine liver which are highly enriched in mannose 6-phosphate receptors. [PDF]
Donald J. Messner+2 more
openalex +1 more source
Characterization of dairy–cereal grain‐based probiotic beverage (Raabadi) powder. ABSTRACT There is gaining interest in innovative instant probiotic food powders with the benefits of dairy and plant food matrices to meet the growing demand for sustainable and healthy probiotic food options.
Kamalesh Kumar Meena+5 more
wiley +1 more source
This review provides a detailed description of gene mutations and epigenetic mechanisms in central nervous system (CNS) disease, strategies for gene therapy, challenges for CNS gene therapy and gene‐drug nanocarriers. This review also summarizes the applications of nanogenetic therapy platforms in CNS diseases (brain tumors, neurodegenerative diseases,
Fuming Liang+4 more
wiley +1 more source