Results 131 to 140 of about 112,119 (302)

Sustainable production of exopolysaccharides from quinoa stalk hydrolysates using halotolerant Bacillus swezeyi: fermentation kinetics and product characterization

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Microbial exopolysaccharides (EPSs) have attracted increasing attention due to their versatile applications across diverse areas. However, large‐scale production of EPSs remains challenging due to the high production costs, primarily driven by the use of synthetic carbon sources.
Diego A. Miranda, Cristhian Carrasco, Luis Romero‐Soto, Jenny Lundqvist, Ola Sundman, Mattias Hedenström, András Gorzsás, Markus Broström, Leif J. Jönsson, Carlos Martín   +9 more
wiley   +1 more source

A Surface Plasmon Resonance‐Based Integrated Assay for Quantification and Glycosylation Characterization of Monoclonal Antibodies in Crude Heterogeneous Samples

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The rise in cancer, autoimmune, inflammatory, and infectious diseases in recent decades has led to a surge in the development of monoclonal antibodies (mAbs) therapies, now the most widely used family of biologics. To meet the growing global demand, biopharmaceutical industries are intensifying their production processes.
Ilona Metayer, Catherine Forest‐Nault, Julie Guimond, Simon Joubert, Olivier Henry, Yves Durocher, Gregory De Crescenzo, Jimmy Gaudreault   +7 more
wiley   +1 more source

Genetic Divergence and Antibody Expression Influence the N‐Glycomes of CHO‐K1 and CHO‐S Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT While Chinese hamster ovary (CHO) cells continue to be the workhorse of recombinant therapeutic protein production, decades of genetic divergence in the industrially relevant CHO‐K1 and CHO‐S cell lines, are likely to have resulted in differing glycosylation capabilities. Glycosylation can influence the efficacy, serum half‐life, and safety of
Roberto Donini, Pat Blundell, Richard J. Pleass, Dongli Lu, Anne Dell, Cleo Kontoravdi, Stuart M. Haslam   +6 more
wiley   +1 more source

Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine. [PDF]

, 1984
Wendy J. Brown, E Constantinescu, M G Farquhar   +2 more
openalex   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Accumulation of coated vesicles bearing mannose 6-phosphate receptors for lysosomal enzymes in the Golgi region of I-cell fibroblasts. [PDF]

, 1984
Wendy J. Brown, M G Farquhar
openalex   +1 more source

Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47

Cancer Communications, EarlyView.
Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang, Chen Zhang, Ruichen Zang, Weiwu Chen, Yining Guo, Haofei Jiang, Jing Le, Kunyu Wang, Haobo Fan, Xudong Wang, Sisi Mo, Peng Gao, Wenhao Guo, Xinrong Jiang, Fengbin Gao, Junming Jiang, Juyan Zheng, Yuxing Chen, Yicheng Chen, Yanlan Yu, Guoqing Ding   +20 more
wiley   +1 more source

Reactivity of Carbohydrate Phosphodiesters, Potential Targets of Antibacterial Agents

Chemistry &Biodiversity, EarlyView.
A simple carbohydrate phosphodiester model was synthesized to compare the reactivity of phosphodiester bonds within carbohydrates and RNA. ABSTRACT While monosaccharide units in bacterial carbohydrates may be linked with phosphodiester bonds, human carbohydrates exclusively contain glycosidic linkages.
Eero Sillanpää, Tuomas Lönnberg, Satu Mikkola   +2 more
wiley   +1 more source

Mannose 6-phosphate-specific receptor is a transmembrane protein with a C-terminal extension oriented towards the cytosol [PDF]

, 1985
Kurt Von Figura, Volkmar Gieselmann, Andrej Hasilík   +2 more
openalex   +1 more source

Chemical Synthesis and Structural Determination of the Inositol Glycan Head of Plant Sphingolipid GIPC in Brassicaceae

Chemistry – A European Journal, EarlyView.
The first experimental identification of the IG head structure of naturally occurring plant GIPCs in Brassicaceae was achieved through the chemical synthesis of three hexose‐type IGs containing d‐glucose, d‐galactose, or d‐mannose as the second monosaccharide linked to d‐glucuronic acid‐α(1→2)‐myo‐inositol.
Yuta Umemura, Majidul Islam, Rumana Yesmin Hasi, Toshiki Ishikawa, Minoru Nagano, Takuji Oka, Naoko Komura, Akihiro Imamura, Hideharu Ishida, Hiromune Ando, Tamotsu Tanaka, Hide‐Nori Tanaka   +11 more
wiley   +1 more source