Results 181 to 190 of about 224,774 (318)

Realizing the promise of ‘La Dolce Vita’ via chemical biology: glycan‐motif editing of sLeX for precision cancer therapeutics

open access: yesThe FEBS Journal, EarlyView.
Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley   +1 more source

Group A Streptococcus interacts with glycosaminoglycans via M proteins to modulate bacterial adherence in vitro

open access: yesThe FEBS Journal, EarlyView.
Interactions between bacteria and the extracellular matrix are a prerequisite for colonisation and infection. Phylogenetically diverse M proteins of group A Streptococcus (GAS) can selectively bind sulfated glycosaminoglycans with high affinity. M protein‐mediated recruitment of chondroitin sulfate and dermatan sulfate was shown to increase GAS ...
Tahnee B.‐D. McEwan   +8 more
wiley   +1 more source

Dysregulation of mannose-6-phosphate-dependent cholesterol homeostasis in acinar cells mediates pancreatitis. [PDF]

open access: yesJ Clin Invest, 2021
Mareninova OA   +17 more
europepmc   +1 more source

Serum Form of the Rat Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor Is Truncated in the Carboxyl-terminal Domain

open access: hybrid, 1989
Richard G. MacDonald   +4 more
openalex   +1 more source

Conversion of G-protein specificity of insulin-like growth factor II/mannose 6-phosphate receptor by exchanging of a short region with beta-adrenergic receptor. [PDF]

open access: green, 1993
Kyôko Takahashi   +8 more
openalex   +1 more source

Anti‐melanogenic effects of Medicago sativa seed extracts on melanocytes

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Our study demonstrated that two types of alfalfa seed extract: alfalfa ethanol precipitate (AEP) and alfalfa ethanol supernatant (AES) inhibited melanogenesis through the downregulation of tyrosinase expression, following the inactivation of CREB, b‐catenin and ERK signalling pathway in α‐melanocyte‐stimulating hormone (α‐MSH)‐stimulated B16F10 mouse ...
Chae Rin Kim   +7 more
wiley   +1 more source

Lrp1/LDL Receptor Play Critical Roles in Mannose 6‐Phosphate‐Independent Lysosomal Enzyme Targeting

open access: yesTraffic : the International Journal of Intracellular Transport, 2015
S. Markmann   +9 more
semanticscholar   +1 more source

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