Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley +1 more source
Publisher Correction: Sortilin knock-down alters the expression and distribution of cathepsin D and prosaposin and up-regulates the cation-dependent mannose-6-phosphate receptor in rat epididymal cells. [PDF]
Aguilera AC+7 more
europepmc +1 more source
Mannose 6-phosphate potentiates insulin-like growth factor II effects in cultured human neuroblastoma cells [PDF]
Eva L. Feldman, Ann Randolph
openalex +1 more source
Interactions between bacteria and the extracellular matrix are a prerequisite for colonisation and infection. Phylogenetically diverse M proteins of group A Streptococcus (GAS) can selectively bind sulfated glycosaminoglycans with high affinity. M protein‐mediated recruitment of chondroitin sulfate and dermatan sulfate was shown to increase GAS ...
Tahnee B.‐D. McEwan+8 more
wiley +1 more source
Dysregulation of mannose-6-phosphate-dependent cholesterol homeostasis in acinar cells mediates pancreatitis. [PDF]
Mareninova OA+17 more
europepmc +1 more source
Conversion of G-protein specificity of insulin-like growth factor II/mannose 6-phosphate receptor by exchanging of a short region with beta-adrenergic receptor. [PDF]
Kyôko Takahashi+8 more
openalex +1 more source
Anti‐melanogenic effects of Medicago sativa seed extracts on melanocytes
Our study demonstrated that two types of alfalfa seed extract: alfalfa ethanol precipitate (AEP) and alfalfa ethanol supernatant (AES) inhibited melanogenesis through the downregulation of tyrosinase expression, following the inactivation of CREB, b‐catenin and ERK signalling pathway in α‐melanocyte‐stimulating hormone (α‐MSH)‐stimulated B16F10 mouse ...
Chae Rin Kim+7 more
wiley +1 more source
Divergent Impact of Enzyme Replacement Therapy on Human Cardiomyocytes and Enterocytes Affected by Fabry Disease: Correlation with Mannose-6-phosphate Receptor Expression. [PDF]
Frustaci A+8 more
europepmc +1 more source
Lrp1/LDL Receptor Play Critical Roles in Mannose 6‐Phosphate‐Independent Lysosomal Enzyme Targeting
S. Markmann+9 more
semanticscholar +1 more source