Results 91 to 100 of about 87,443 (234)

Proteomics analysis of serum protein profiling in pancreatic cancer patients by DIGE: up-regulation of mannose-binding lectin 2 and myosin light chain kinase 2

BMC Gastroenterology, 2010
Background Pancreatic cancer has significant morbidity and mortality worldwide. Good prognosis relies on an early diagnosis. The purpose of this study was to develop techniques for identifying cancer biomarkers in the serum of patients with pancreatic ...
Ni Xiaolin, Wu Wenchuan, Hu Jianwen, Hou Chenrui, Jin Dayong, Rong Yefei, Wang Dansong, Lou Wenhui   +7 more
doaj   +1 more source

Mannose-Binding Lectin Binds to Amyloid β Protein and Modulates Inflammation

Journal of Biomedicine and Biotechnology, 2012
Mannose-binding lectin (MBL), a soluble factor of the innate immune system, is a pattern recognition molecule with a number of known ligands, including viruses, bacteria, and molecules from abnormal self tissues.
M. Larvie, T. Shoup, Wei‐Chuan Chang, Lorencia Chigweshe, K. Hartshorn, M. White, G. Stahl, D. Elmaleh, Kazue Takahashi   +8 more
semanticscholar   +1 more source

Nanotechnology‐Based Immunostimulants in Aquaculture: Mechanisms, Advances and Practical Applications

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nano‐immunostimulants improve fish health through targeted and controlled delivery of immunostimulatory compounds. Biodegradable polymeric and lipid‐based nanocarriers enhance immune responses, bioavailability and disease resistance while reducing antibiotic dependence and environmental impact.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

Impact of bacterial vaginosis, as assessed by nugent criteria and hormonal status on glycosidases and lectin binding in cervicovaginal lavage samples.

PLoS ONE, 2015
The objective of this study was to evaluate the impact of hormonal status and bacterial vaginosis (BV) on the glycosidases present and glycosylation changes as assessed by lectin binding to cervicovaginal lavage constituents. Frozen cervicovaginal lavage
Bernard J Moncla, Catherine A Chappell, Lara K Mahal, Brian M Debo, Leslie A Meyn, Sharon L Hillier   +5 more
doaj   +1 more source

Identification of potential urine proteins and microRNA biomarkers for the diagnosis of pulmonary tuberculosis patients

Emerging Microbes and Infections, 2018
This study identified urinary biomarkers for tuberculosis (TB) diagnosis. The urine proteomic profiles of 45 pulmonary tuberculosis patients prior to anti-TB treatment and 45 healthy controls were analyzed and compared using two-dimensional ...
Jieru Wang, Xiaojie Zhu, Xuekai Xiong, Pan Ge, Han Liu, Ningning Ren, Farhan Anwar Khan, Xia Zhou, Li Zhang, Xu Yuan, Xi Chen, Yingyu Chen, Changmin Hu, Ian D. Robertson, Huanchun Chen, Aizhen Guo   +15 more
doaj   +1 more source

High-Mannose Specific Lectin and Its Recombinants from a Carrageenophyta Kappaphycus alvarezii Represent a Potent Anti-HIV Activity Through High-Affinity Binding to the Viral Envelope Glycoprotein gp120

Marine Biotechnology, 2015
We previously reported that a high-mannose binding lectin KAA-2 from the red alga Kappaphycus alvarezii, which is an economically important species and widely cultivated as a source of carrageenans, had a potent anti-influenza virus activity.
M. Hirayama, H. Shibata, K. Imamura, T. Sakaguchi, K. Hori   +4 more
semanticscholar   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Bacterial surface display of human lectins in Escherichia coli

Microbial Biotechnology
Lectin‐glycan interactions sustain fundamental biological processes involved in development and disease. Owing to their unique sugar‐binding properties, lectins have great potential in glycobiology and biomedicine.
Alba Vázquez‐Arias, Lorena Vázquez‐Iglesias, Ignacio Pérez‐Juste, Jorge Pérez‐Juste, Isabel Pastoriza‐Santos, Gustavo Bodelon   +5 more
doaj   +1 more source

Glycan microarray analysis of the carbohydrate-recognition specificity of native and recombinant forms of the lectin ArtinM

Data in Brief, 2015
This article contains data related to the researc.h article entitled “Yeast-derived ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM” by Cecílio et al. (2015) [1].
Y. Liu, N.T. Cecílio, F.C. Carvalho, M.C. Roque-Barreira, T. Feizi   +4 more
doaj   +1 more source

Secondary Cell Wall Polymers of Enterococcus faecalis Are Critical for Resistance to Complement Activation via Mannose-binding Lectin*

Journal of Biological Chemistry, 2012
Background: Little is known about the complement evasion strategies of Enterococcus faecalis. Results: Inactivation of tagB in E. faecalis V583 resulted in the loss of two wall teichoic acids (WTAs) associated with a strongly increased complement ...
Stefan Geiss-Liebisch, S. Rooijakkers, Agnieszka Beczała, Patricia M Sánchez-Carballo, Karolina Kruszynska, Christian Repp, Tuerkan Sakinc, E. Vinogradov, O. Holst, J. Huebner, C. Theilacker   +10 more
semanticscholar   +1 more source