Results 221 to 230 of about 82,856 (307)

Deciphering epigenetic regulation in postmenopausal osteoporosis: Current and future perspectives

open access: yesVIEW, EarlyView.
In this perspective, the significant roles of microRNAs, long noncoding RNAs and circular RNAs in postmenopausal osteoporosis are thoroughly expounded. The advantages and limitations of typical noncoding RNAs as diagnostic biomarkers and therapeutic targets are summarized and discussed.
Xiumei Tang   +10 more
wiley   +1 more source

DLD‐HLNP/P@IR780 for efficient lung‐parenchyma accumulation to treat idiopathic pulmonary fibrosis

open access: yesVIEW, EarlyView.
DLD‐HLNP/P@IR780 was synthesized to target to lung and treat IPF by releasing pirfenidone. It could effectively traverse pulmonary ECB and accumulate in lung parenchyma by IR780 binding to CD300LF and MRC1 which are abundantly and specifically expressed on pulmonary endothelial cell and pulmonary macrophages.
Mengzhu Wang   +3 more
wiley   +1 more source

Mannose receptor targeted bioadhesive chitosan nanoparticles of clofazimine for effective therapy of tuberculosis. [PDF]

open access: yesSaudi Pharm J, 2020
Pawde DM   +12 more
europepmc   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Sandra M. Skovdal   +5 more
wiley   +1 more source

Transcriptional regulation of the HIV-1 inhibitory factor human mannose receptor 1 by the myeloid-specific transcription factor PU.1. [PDF]

open access: yesJ Virol
Mallorson R   +9 more
europepmc   +1 more source

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