Results 1 to 10 of about 38,043 (146)

Biotechnological Applications of C-Type Lectins Isolated from Snake Venoms [PDF]

Molecules
Snake venoms are rich sources of molecules with pharmacological potential, with approximately 90% of their composition consisting of proteins and peptides responsible for their biological activities.
Ellynes Amancio Correia Nunes, Geovanna Moura, Breno Emanuel Farias Frihling, Juliana Ferreira de Lima, Adriel Parahyba Lacerda, Rayane Vasconcelos, Ana Paula de Araújo Boleti, Ana Cristina Jacobowski, Juliana Zuliani, Elizeu Antunes dos Santos, Hector Koolen, Karla Luna, Maria Ligia Rodrigues de Macedo, Ludovico Migliolo   +13 more
doaj   +2 more sources

Signalling C-type lectins in antimicrobial immunity.

PLoS Pathogens, 2013
Since it was first proposed that the innate immune system could recognise conserved microbial-associated molecular patterns (or PAMPs) through inherited receptors expressed by the host (termed pattern recognition receptors, or PRRs), several families of PRRs have been discovered and characterised.
Rebecca A Drummond, Gordon D Brown
doaj   +5 more sources

C-Type Lectins from Marine Bivalves: Functional Diversity and Structural Insights [PDF]

Marine Drugs
C-type lectins (CTLs) are a large family of calcium-dependent carbohydrate-binding proteins that play crucial roles in innate immunity as pattern recognition receptors.
Ivan Buriak, Daria Lanskikh, Ivan Baklanov, Daniil Kozyrev, Andrei Grinchenko   +4 more
doaj   +2 more sources

Molecular Cloning and Characteristics of a Lectin from the Bivalve Glycymeris yessoensis

Marine Drugs, 2023
C-type lectins (CTLs) are a family of carbohydrate-binding proteins that mediate multiple biological events, including adhesion between cells, the turnover of serum glycoproteins, and innate immune system reactions to prospective invaders.
Tatyana O. Mizgina, Sergey N. Baldaev, Galina N. Likhatskaya, Valentina I. Molchanova, Maxim S. Kokoulin, Alina P. Filshtein, Eugene A. Rogozhin, Irina V. Chikalovets, Marina P. Isaeva, Oleg V. Chernikov   +9 more
doaj   +1 more source

An Update of Lectins from Marine Organisms: Characterization, Extraction Methodology, and Potential Biofunctional Applications

Marine Drugs, 2022
Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycoproteins that exhibit specific and reversible carbohydrate-binding activity in a non-catalytic manner.
Mirja Kaizer Ahmmed, Shuva Bhowmik, Stephen G. Giteru, Md. Nazmul Hasan Zilani, Parise Adadi, Shikder Saiful Islam, Osman N. Kanwugu, Monjurul Haq, Fatema Ahmmed, Charlene Cheuk Wing Ng, Yau Sang Chan, Md. Asadujjaman, Gabriel Hoi Huen Chan, Ryno Naude, Alaa El-Din Ahmed Bekhit, Tzi Bun Ng, Jack Ho Wong   +16 more
doaj   +1 more source

A Genomic and Transcriptomic Analysis of the C-Type Lectin Gene Family Reveals Highly Expanded and Diversified Repertoires in Bivalves

Marine Drugs, 2023
C-type lectins belong to a widely conserved family of lectins characterized in Metazoa. They show important functional diversity and immune implications, mainly as pathogen recognition receptors.
Amaro Saco, Hugo Suárez, Beatriz Novoa, Antonio Figueras   +3 more
doaj   +1 more source

Can Plant Lectins Help to Elucidate Insect Lectin-Mediated Immune Response?

Insects, 2021
Lectins are carbohydrate-binding proteins that recognize and selectively bind to specific sugar structures. This group of proteins is widespread in plants, animals, and microorganisms, and exerts a broad range of functions.
Pengyu Chen, Kristof De Schutter, Els J. M. Van Damme, Guy Smagghe   +3 more
doaj   +1 more source

C-Type Lectin Receptors in Asthma [PDF]

Frontiers in Immunology, 2018
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Sabelo Hadebe, Sabelo Hadebe, Frank Brombacher, Frank Brombacher, Gordon D. Brown, Gordon D. Brown   +5 more
openaire   +4 more sources

Information transfer in mammalian glycan-based communication

eLife, 2023
Glycan-binding proteins, so-called lectins, are exposed on mammalian cell surfaces and decipher the information encoded within glycans translating it into biochemical signal transduction pathways in the cell.
Felix F Fuchsberger, Dongyoon Kim, Natalia Baranova, Hanka Vrban, Marten Kagelmacher, Robert Wawrzinek, Christoph Rademacher   +6 more
doaj   +1 more source

C-type lectins and extracellular vesicles in virus-induced NETosis

Journal of Biomedical Science, 2021
Dysregulated formation of neutrophil extracellular traps (NETs) is observed in acute viral infections. Moreover, NETs contribute to the pathogenesis of acute viral infections, including those caused by the dengue virus (DV) and severe acute respiratory ...
Pei-Shan Sung, Shie-Liang Hsieh
doaj   +1 more source