C-type lectin receptors in skin immunity: Emerging new role for CLEC12B
Advances in Biomedical and Health Sciences, 2022 C-type lectin receptors (CLRs) are a superfamily of transmembrane proteins, which consist of one or several C-type lectin-like domains and intracellular signaling motifs, such as immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor ...
Lauriane Blot +2 more
doaj +1 more source
C-type lectin receptors orchestrate antifungal immunity [PDF]
Nature Immunology, 2012 Immunity to pathogens critically requires pattern-recognition receptors (PRRs) to trigger intracellular signaling cascades that initiate and direct innate and adaptive immune responses. For fungal infections, these responses are primarily mediated by members of the C-type lectin receptor family.
Sarah E, Hardison, Gordon D, Brown
openaire +2 more sources
Role of Lectin in the Response of Aedes aegypti Against Bt Toxin
Frontiers in Immunology, 2022 Aedes aegypti is one of the world’s most dangerous mosquitoes, and a vector of diseases such as dengue fever, chikungunya virus, yellow fever, and Zika virus disease.
Intikhab Alam +11 more
doaj +1 more source
The Third Dimension of Reading the Sugar Code by Lectins [PDF]
, 2013 Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
André, Sabine +2 more
core +3 more sources
Glycotope structures and intramolecular affinity factors of plant lectins for Tn/T antigens [PDF]
, 2011 B
A Babino +42 more
core +3 more sources
Integrative analysis workflow for the structural and functional classification of C-type lectins
BMC Bioinformatics, 2011 Background It is important to understand the roles of C-type lectins in the immune system due to their ubiquity and diverse range of functions in animal cells.
Koh Geoffrey +8 more
doaj +1 more source
The Roles of Direct Recognition by Animal Lectins in Antiviral Immunity and Viral Pathogenesis
Molecules, 2015 Lectins are a group of proteins with carbohydrate recognition activity. Lectins are categorized into many families based on their different cellular locations as well as their specificities for a variety of carbohydrate structures due to the features of ...
Yang Liu +5 more
doaj +1 more source
FGB1 and WSC3 are in planta-induced beta-glucan-binding fungal lectins with different functions [PDF]
, 2019 In the root endophyte Serendipita indica, several lectin-like members of the expanded multigene family of WSC proteins are transcriptionally induced in planta and are potentially involved in beta-glucan remodeling at the fungal cell wall.
Becker, S. +8 more
core +2 more sources
OsEUL lectin gene expression in rice : stress regulation, subcellular localization and tissue specificity [PDF]
, 2020 The Euonymus lectin (EUL) family is a unique group of carbohydrate-binding proteins that is omnipresent in plants. Sequences encoding EUL-related lectins have been retrieved from all completely sequenced plant genomes.
De Zaeytijd, Jeroen +9 more
core +1 more source
C-type lectins facilitate tumor metastasis
Oncology Letters, 2016 Metastasis, a life-threatening complication of cancer, leads to the majority of cases of cancer-associated mortality. Unfortunately, the underlying molecular and cellular mechanisms of cancer metastasis remain to be fully elucidated. C-type lectins are a large group of proteins, which share structurally homologous carbohydrate-recognition domains (CRDs)
Ding, Dongbing +4 more
openaire +3 more sources