Results 1 to 10 of about 69,976 (338)
Signalling C-type lectins in antimicrobial immunity. [PDF]
PLoS Pathogens, 2013 Funding: This work was funded by the Wellcome Trust, Medical Research Council and the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Rebecca A Drummond, Gordon D Brown
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C-type lectins and extracellular vesicles in virus-induced NETosis [PDF]
Journal of Biomedical Science, 2021 Dysregulated formation of neutrophil extracellular traps (NETs) is observed in acute viral infections. Moreover, NETs contribute to the pathogenesis of acute viral infections, including those caused by the dengue virus (DV) and severe acute respiratory ...
Pei-Shan Sung, Shie-Liang Hsieh
doaj +2 more sources
C-Type Lectins Link Immunological and Reproductive Processes in Aedes aegypti [PDF]
iScience, 2020 Summary: Physiological trade-offs between mosquito immune response and reproductive capability can arise due to insufficient resource availability. C-type lectin family members may be involved in these processes.
Hsing-Han Li +9 more
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Aquaculture Reports, 2022 C-type lectins are pattern recognition receptors (PRRs) involved in innate immunity. They possess one or more carbohydrate recognition domains (CRDs) belonging to Ca2+-dependent carbohydrate binding proteins.
Jingwen Liu +8 more
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Molecular basis for intestinal mucin recognition by galectin-3 and C-type lectins. [PDF]
FASEB J, 2018 Intestinal mucins trigger immune responses upon recognition by dendritic cells via protein–carbohydrate interactions. We used a combination of structural, biochemical, biophysical, and cell-based approaches to decipher the specificity of the interaction ...
Leclaire C +9 more
europepmc +2 more sources
C-Type Lectins from Marine Bivalves: Functional Diversity and Structural Insights [PDF]
Marine DrugsC-type lectins (CTLs) are a large family of calcium-dependent carbohydrate-binding proteins that play crucial roles in innate immunity as pattern recognition receptors.
Ivan Buriak +4 more
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Syk-coupled C-type lectins in immunity [PDF]
Trends in Immunology, 2011 The Syk-coupled C-type lectin receptor Dectin-1 was the first non-Toll like receptor described that could mediate its own intracellular signalling. It was initially identified as important for the innate recognition of and response to fungal pathogens but later studies revealed that it is also involved in triggering adaptive immune responses.
Ann M. Kerrigan, Gordon D. Brown
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C-type lectins facilitate tumor metastasis. [PDF]
Oncol Lett, 2017 Metastasis, a life-threatening complication of cancer, leads to the majority of cases of cancer-associated mortality. Unfortunately, the underlying molecular and cellular mechanisms of cancer metastasis remain to be fully elucidated. C-type lectins are a large group of proteins, which share structurally homologous carbohydrate-recognition domains (CRDs)
Ding D, Yao Y, Zhang S, Su C, Zhang Y.
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CD209 C-Type Lectins Promote Host Invasion, Dissemination, and Infection of Toxoplasma gondii [PDF]
Frontiers in Immunology, 2020 Toxoplasma gondii, the causative agent of toxoplasmosis and a major opportunistic parasite associated with AIDS, is able to invade host cells of animals and humans.
Olivia Adhiambo Njiri +8 more
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From Snake Venom’s Disintegrins and C-Type Lectins to Anti-Platelet Drugs [PDF]
Toxins, 2019 Snake venoms are attractive natural sources for drug discovery and development, with a number of substances either in clinical use or in research and development.
Philip Lazarovici +2 more
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