Results 31 to 40 of about 24,419,878 (289)

Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin

Toxins, 2011
The entry of ricin toxin into macrophages and certain other cell types in the spleen and liver results in toxin-induced inflammation, tissue damage and organ failure.
Emily Gage, Maria O. Hernandez, Joanne M. O’Hara, Elizabeth A. McCarthy, Nicholas J. Mantis   +4 more
doaj   +1 more source

Functional characterisation and comparative analysis of two C-type lectins with different key motifs from mud crab

Aquaculture Reports, 2022
C-type lectins are pattern recognition receptors (PRRs) involved in innate immunity. They possess one or more carbohydrate recognition domains (CRDs) belonging to Ca2+-dependent carbohydrate binding proteins.
Jingwen Liu, Xiaocong Lou, Yuying Yang, Xiaoyuan Zheng, Yunkai Zhang, Peng Zhou, Shun Yang, Mengmeng Huang, Hui Fei   +8 more
doaj   +1 more source

Synthesis of a multivalent α-1,2-mannobiose ligand for targeting C-type lectins. [PDF]

RSC Adv
The importance of lectins in biological processes such as pathogen recognition, cell adhesion, and cell recognition is well documented. C-Type lectins, which require calcium for binding, play an important role in the innate immune response by engaging ...
Langer J, Hartmann L, Snyder NL.
europepmc   +2 more sources

Lectin ligands: New insights into their conformations and their dynamic behavior and the discovery of conformer selection by lectins [PDF]

, 1998
The mysteries of the functions of complex glycoconjugates have enthralled scientists over decades. Theoretical considerations have ascribed an enormous capacity to store information to oligosaccharides, In the interplay with lectins sugar-code words of ...
Kozár, T., Frank, M., Gabius, H.-J., Kaltner, Herbert, Bovin, Nicolai V., Lieth, C.-W. von der, Burchert, M., Tajkhorshid, Emadeddin, Gilleron, M., Siebert, H.-C., Tajkhorshid, E., Kayser, Gian, Siebert, H. C., Vliegenthart, JFG, Vliegenthart, J.F.G., Bovin, N.V., Vliegenthart, Johannes F. G., Gabius, Hans-Joachim, Bovin, N. V., Burchert, Maria, Kaltner, H., Gilleron, Martine, von Der Lieth, C.-W., Kayser, G., Tajkhorshid, Emad, Lieth, Claus-Wilhelm von der, Leith, C.-W. von der, N.V. Bovin, J.F.G. Vliegenthart, C.-W. von der Lieth, T. Kožár, M. Frank, E. Tajkhorshid, H.-C. Siebert, M. Gilleron, H. Kaltner, M. Burchert, H.-J. Gabius, G. Kayser   +38 more
core   +2 more sources

Immune characterization and expression analysis of a C-type lectin from Pinctada fucata martensii

Aquaculture Reports, 2023
C-type lectins are involved in nonself-recognition and pathogen clearance, and play an important role in innate immunity. Pinctada fucata martensii, which is an important shellfish in the pearl industry, is being attacked by pathogenic microorganisms ...
Zhijie Guo, Miao Xie, Chenghao Shen, Haiying Liang, Chaojie Li, Yifan Wu   +5 more
doaj   +1 more source

C-type lectins in immunity and homeostasis

Nature Reviews Immunology, 2018
The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands and that regulate a diverse range of physiological functions. Most research attention has focused on the ability of C-type lectins to function in innate and adaptive antimicrobial immune responses, but these proteins are increasingly being recognized to have a
Brown, Gordon D, Willment, Janet A, Whitehead, Lauren   +2 more
openaire   +4 more sources

Towards defining the role of glycans as hardware in information storage and transfer: Basic principles, experimental approaches and recent progress [PDF]

, 2001
The term `code' in biological information transfer appears to be tightly and hitherto exclusively connected with the genetic code based on nucleotides and translated into functional activities via proteins.
Jiménez-Barbero, J., Romero, A., Gabius, Hans-Joachim, Siebert, H.-C., Solís, Dolores, Kaltner, H., Lieth, Claus-Wilhelm von der   +6 more
core   +1 more source

L-Type lectins [PDF]

, 2022
The L-type lectins occur in the seeds of leguminous plants. They have structural motifs present in a variety of glycan-binding proteins (GBPs) from other eukaryotic organisms.
Cummings, Richard D., Rabinovich, Gabriel Adrián, Surolia, Avadhesha, Ramya, T. N. C., Etzler, Marilynn E., Kato, Koichi   +5 more
core   +1 more source

C-type lectin receptors in skin immunity: Emerging new role for CLEC12B

Advances in Biomedical and Health Sciences, 2022
C-type lectin receptors (CLRs) are a superfamily of transmembrane proteins, which consist of one or several C-type lectin-like domains and intracellular signaling motifs, such as immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor ...
Lauriane Blot, Thierry Passeron, Meri K Tulic   +2 more
doaj   +1 more source

Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]

, 1998
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Korabiowska, M., Brinck, U., Bosbach, R., Gabius, Hans-Joachim   +3 more
core   +1 more source