Results 21 to 30 of about 38,156 (249)
C-type lectins and phagocytosis
Immunobiology, 2009 To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
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The immune role of C-type lectins in molluscs [PDF]
Invertebrate Survival Journal, 2011 The phylum Mollusca is one of the largest and most important group in the animal kingdom. Recently, interest in molluscan immunity has increased due to their importance in worldwide aquaculture, their role in aquatic environmental science and their ...
L Wang, L Wang, M Huang, H Zhang, L Song
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Aquaculture Reports, 2022 C-type lectins are pattern recognition receptors (PRRs) involved in innate immunity. They possess one or more carbohydrate recognition domains (CRDs) belonging to Ca2+-dependent carbohydrate binding proteins.
Jingwen Liu +8 more
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Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin
Toxins, 2011 The entry of ricin toxin into macrophages and certain other cell types in the spleen and liver results in toxin-induced inflammation, tissue damage and organ failure.
Emily Gage +4 more
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C-type lectins in immunity: recent developments. [PDF]
Curr Opin Immunol, 2015 C-type lectin receptors (CLRs) comprise a large superfamily of proteins, which recognise a diverse range of ligands, and are defined by the presence of at least one C-type lectin-like domain (CTLD). Of particular interest are the single extracellular CTLD-containing receptors of the 'Dectin-1' and 'Dectin-2' clusters, which associate with signalling ...
Dambuza IM, Brown GD.
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Immune characterization and expression analysis of a C-type lectin from Pinctada fucata martensii
Aquaculture Reports, 2023 C-type lectins are involved in nonself-recognition and pathogen clearance, and play an important role in innate immunity. Pinctada fucata martensii, which is an important shellfish in the pearl industry, is being attacked by pathogenic microorganisms ...
Zhijie Guo +5 more
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C-type lectins in immunity and homeostasis
Nature Reviews Immunology, 2018 The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands and that regulate a diverse range of physiological functions. Most research attention has focused on the ability of C-type lectins to function in innate and adaptive antimicrobial immune responses, but these proteins are increasingly being recognized to have a
Brown, Gordon D +2 more
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C-type lectin receptors in skin immunity: Emerging new role for CLEC12B
Advances in Biomedical and Health Sciences, 2022 C-type lectin receptors (CLRs) are a superfamily of transmembrane proteins, which consist of one or several C-type lectin-like domains and intracellular signaling motifs, such as immunoreceptor tyrosine-based activation motif (ITAM) or immunoreceptor ...
Lauriane Blot +2 more
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Integrative analysis workflow for the structural and functional classification of C-type lectins
BMC Bioinformatics, 2011 Background It is important to understand the roles of C-type lectins in the immune system due to their ubiquity and diverse range of functions in animal cells.
Koh Geoffrey +8 more
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Role of Lectin in the Response of Aedes aegypti Against Bt Toxin
Frontiers in Immunology, 2022 Aedes aegypti is one of the world’s most dangerous mosquitoes, and a vector of diseases such as dengue fever, chikungunya virus, yellow fever, and Zika virus disease.
Intikhab Alam +11 more
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