Results 21 to 30 of about 24,419,878 (289)
C-Type Lectin Receptors in Asthma [PDF]
Frontiers in Immunology, 2018 Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Sabelo Hadebe +5 more
openaire +4 more sources
Information transfer in mammalian glycan-based communication
eLife, 2023 Glycan-binding proteins, so-called lectins, are exposed on mammalian cell surfaces and decipher the information encoded within glycans translating it into biochemical signal transduction pathways in the cell.
Felix F Fuchsberger +6 more
doaj +1 more source
Animal lectins as cell adhesion molecules [PDF]
, 1998 Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core +1 more source
C-type lectins and phagocytosis
Immunobiology, 2009 To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several ...
Kerrigan, Ann, Brown, Gordon D
openaire +3 more sources
C-type lectins in immunity: recent developments. [PDF]
Curr Opin Immunol, 2015 C-type lectin receptors (CLRs) comprise a large superfamily of proteins, which recognise a diverse range of ligands, and are defined by the presence of at least one C-type lectin-like domain (CTLD). Of particular interest are the single extracellular CTLD-containing receptors of the 'Dectin-1' and 'Dectin-2' clusters, which associate with signalling ...
Dambuza IM, Brown GD.
europepmc +4 more sources
Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]
, 2005 Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Szöke, Tamas +9 more
core +1 more source
Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention. [PDF]
PLoS Pathogens, 2014 C-type lectins are a family of proteins with carbohydrate-binding activity. Several C-type lectins in mammals or arthropods are employed as receptors or attachment factors to facilitate flavivirus invasion.
Yang Liu +8 more
doaj +1 more source
Solution structure, glycan specificity and of phenol oxidase inhibitory activity of Anopheles C-type lectins CTL4 and CTLMA2. [PDF]
Sci Rep, 2019 Malaria, the world’s most devastating parasitic disease, is transmitted between humans by mosquitoes of the Anopheles genus. An. gambiae is the principal malaria vector in Sub-Saharan Africa.
Bishnoi R +10 more
europepmc +2 more sources
The immune role of C-type lectins in molluscs [PDF]
Invertebrate Survival Journal, 2011 The phylum Mollusca is one of the largest and most important group in the animal kingdom. Recently, interest in molluscan immunity has increased due to their importance in worldwide aquaculture, their role in aquatic environmental science and their ...
L Wang, L Wang, M Huang, H Zhang, L Song
doaj +1 more source
The Third Dimension of Reading the Sugar Code by Lectins [PDF]
, 2013 Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
Murphy, Paul +7 more
core +1 more source