Lectins with Potential for Anti-Cancer Therapy
Molecules, 2015 This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins,
Tammy Yau +3 more
doaj +3 more sources
Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention. [PDF]
PLoS Pathogens, 2014 C-type lectins are a family of proteins with carbohydrate-binding activity. Several C-type lectins in mammals or arthropods are employed as receptors or attachment factors to facilitate flavivirus invasion.
Yang Liu +8 more
doaj +2 more sources
Targeting the C-type Lectins-Mediated Host-Pathogen Interactions with Dextran [PDF]
Journal of Pharmacy & Pharmaceutical Sciences, 2014 Dextran, the α-1,6-linked glucose polymer widely used in biology and medicine, promises new applications. Linear dextran applied as a blood plasma substitute demonstrates a high rate of biocompatibility.
Sergey Pustylnikov +3 more
doaj +2 more sources
C-type lectins in immunity and homeostasis
Nature Reviews Immunology, 2018 The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands and that regulate a diverse range of physiological functions. Most research attention has focused on the ability of C-type lectins to function in innate and adaptive antimicrobial immune responses, but these proteins are increasingly being recognized to have a
Brown, Gordon D +2 more
openaire +6 more sources
C-type lectins in immunity: recent developments. [PDF]
Curr Opin Immunol, 2015 C-type lectin receptors (CLRs) comprise a large superfamily of proteins, which recognise a diverse range of ligands, and are defined by the presence of at least one C-type lectin-like domain (CTLD). Of particular interest are the single extracellular CTLD-containing receptors of the 'Dectin-1' and 'Dectin-2' clusters, which associate with signalling ...
Dambuza IM, Brown GD.
europepmc +4 more sources
Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1. [PDF]
PLoS ONE, 2017 Phagocytosis by innate immune cells is an important process for protection against multiple pathologies and is particularly important for resistance to infection.
Naomi M Walsh +4 more
doaj +2 more sources
Parasitic infections: a role for C-type lectins receptors. [PDF]
Biomed Res Int, 2013 Vázquez-Mendoza A +2 more
europepmc +3 more sources
Chimeric RNA isoforms generated by diverse mechanisms from two C-type lectins modulate innate immunity in arthropods. [PDF]
Proc Natl Acad Sci U S AHuang Y, Huang X, Zhang LH, Ren Q.
europepmc +3 more sources
C-type lectins in HIV-1 infection [PDF]
Retrovirology, 2011 Geijtenbeek Teunis BH
doaj +2 more sources
Molecular Cloning and Characteristics of a Lectin from the Bivalve Glycymeris yessoensis
Marine Drugs, 2023 C-type lectins (CTLs) are a family of carbohydrate-binding proteins that mediate multiple biological events, including adhesion between cells, the turnover of serum glycoproteins, and innate immune system reactions to prospective invaders.
Tatyana O. Mizgina +9 more
doaj +1 more source