Results 11 to 20 of about 38,156 (249)
Signalling C-type lectins in antimicrobial immunity. [PDF]
PLoS Pathogens, 2013 Since it was first proposed that the innate immune system could recognise conserved microbial-associated molecular patterns (or PAMPs) through inherited receptors expressed by the host (termed pattern recognition receptors, or PRRs), several families of PRRs have been discovered and characterised.
Rebecca A Drummond, Gordon D Brown
doaj +6 more sources
Targeting the C-type Lectins-Mediated Host-Pathogen Interactions with Dextran [PDF]
Journal of Pharmacy & Pharmaceutical Sciences, 2014 Dextran, the α-1,6-linked glucose polymer widely used in biology and medicine, promises new applications. Linear dextran applied as a blood plasma substitute demonstrates a high rate of biocompatibility.
Sergey Pustylnikov +3 more
doaj +2 more sources
Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1. [PDF]
PLoS ONE, 2017 Phagocytosis by innate immune cells is an important process for protection against multiple pathologies and is particularly important for resistance to infection.
Naomi M Walsh +4 more
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C-type lectins in HIV-1 infection [PDF]
Retrovirology, 2011 Geijtenbeek Teunis BH
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Molecular Cloning and Characteristics of a Lectin from the Bivalve Glycymeris yessoensis
Marine Drugs, 2023 C-type lectins (CTLs) are a family of carbohydrate-binding proteins that mediate multiple biological events, including adhesion between cells, the turnover of serum glycoproteins, and innate immune system reactions to prospective invaders.
Tatyana O. Mizgina +9 more
doaj +1 more source
C-type lectins facilitate tumor metastasis. [PDF]
Oncol Lett, 2017 Metastasis, a life-threatening complication of cancer, leads to the majority of cases of cancer-associated mortality. Unfortunately, the underlying molecular and cellular mechanisms of cancer metastasis remain to be fully elucidated. C-type lectins are a large group of proteins, which share structurally homologous carbohydrate-recognition domains (CRDs)
Ding D, Yao Y, Zhang S, Su C, Zhang Y.
europepmc +4 more sources
Marine Drugs, 2023 C-type lectins belong to a widely conserved family of lectins characterized in Metazoa. They show important functional diversity and immune implications, mainly as pathogen recognition receptors.
Amaro Saco +3 more
doaj +1 more source
Can Plant Lectins Help to Elucidate Insect Lectin-Mediated Immune Response?
Insects, 2021 Lectins are carbohydrate-binding proteins that recognize and selectively bind to specific sugar structures. This group of proteins is widespread in plants, animals, and microorganisms, and exerts a broad range of functions.
Pengyu Chen +3 more
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C-Type Lectin Receptors in Asthma [PDF]
Frontiers in Immunology, 2018 Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Sabelo Hadebe +5 more
openaire +4 more sources
Information transfer in mammalian glycan-based communication
eLife, 2023 Glycan-binding proteins, so-called lectins, are exposed on mammalian cell surfaces and decipher the information encoded within glycans translating it into biochemical signal transduction pathways in the cell.
Felix F Fuchsberger +6 more
doaj +1 more source