Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention. [PDF]
PLoS Pathogens, 2014 C-type lectins are a family of proteins with carbohydrate-binding activity. Several C-type lectins in mammals or arthropods are employed as receptors or attachment factors to facilitate flavivirus invasion.
Yang Liu +8 more
doaj +1 more source
Crystal Structure of the C-type Lectin-like Domain from the Human Hematopoietic Cell Receptor CD69 [PDF]
, 2001 CD69, one of the earliest specific antigens acquired during lymphoid activation, acts as a signal-transducing receptor involved in cellular activation events, including proliferation and induction of specific genes.
Andrea S. Llera +63 more
core +1 more source
C-Type Lectin Receptors in Asthma [PDF]
Frontiers in Immunology, 2018 Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Sabelo Hadebe +5 more
openaire +4 more sources
Overexpression of Nictaba-like lectin genes from glycine max confers tolerance towards Pseudomonas syringae infection, aphid infestation and salt stress in transgenic Arabidopsis plants [PDF]
, 2016 Plants have evolved a sophisticated immune system that allows them to recognize invading pathogens by specialized receptors. Carbohydrate-binding proteins or lectins are part of this immune system and especially the lectins that reside in the ...
Smagghe, Guy +2 more
core +6 more sources
How C-type lectins detect pathogens. [PDF]
Cellular microbiology, 2005 Glycosylation of proteins has proven extremely important in a variety of cellular processes, including enzyme trafficking, tissue homing and immune functions. In the past decade, increasing interest in carbohydrate-mediated mechanisms has led to the identification of novel carbohydrate-recognizing receptors expressed on cells of the immune system ...
Cambi, A., Koopman, M., Figdor, C.G.
openaire +5 more sources
Molecular basis for intestinal mucin recognition by galectin-3 and C-type lectins [PDF]
, 2018 Intestinal mucins trigger immune responses upon recognition by dendritic cells via protein–carbohydrate interactions. We used a combination of structural, biochemical, biophysical, and cell-based approaches to decipher the specificity of the interaction ...
Gunning, A. Patrick +9 more
core +1 more source
Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. [PDF]
, 2019 Fam20C is a secreted protein kinase mutated in Raine syndrome, a human skeletal disorder. In vertebrates, bone and enamel proteins are major Fam20C substrates.
Adina Gerson-Gurwitz +70 more
core +3 more sources
The immune role of C-type lectins in molluscs [PDF]
Invertebrate Survival Journal, 2011 The phylum Mollusca is one of the largest and most important group in the animal kingdom. Recently, interest in molluscan immunity has increased due to their importance in worldwide aquaculture, their role in aquatic environmental science and their ...
L Wang, L Wang, M Huang, H Zhang, L Song
doaj +1 more source
Aquaculture Reports, 2022 C-type lectins are pattern recognition receptors (PRRs) involved in innate immunity. They possess one or more carbohydrate recognition domains (CRDs) belonging to Ca2+-dependent carbohydrate binding proteins.
Jingwen Liu +8 more
doaj +1 more source
Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]
, 2002 The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Dvorankova, Barbora +7 more
core +1 more source