Results 251 to 260 of about 135,703 (297)

The mannose receptor family

Biochimica et Biophysica Acta (BBA) - General Subjects, 2002
The mannose receptor family comprises four glycoproteins each of which is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single fibronectin type II (FNII) domain and eight to ten C-type lectin-like domains (CTLDs). Characteristically, these proteins are able to recycle between the plasma membrane and the endosomal apparatus ...
Lucy, East, Clare M, Isacke
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Mannose receptor-targeted vaccines

Expert Opinion on Biological Therapy, 2004
Targeting antigens to endocytic receptors on professional antigen-presenting cells (APCs) represents an attractive strategy to enhance the efficacy of vaccines. Such APC-targeted vaccines have an exceptional ability to guide exogenous protein antigens into vesicles that efficiently process the antigen for major histocompatibility complex class I and ...
Tibor, Keler, Venky, Ramakrishna, Michael W, Fanger   +2 more
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Ligand recognition by purified human mannose receptor

Archives of Biochemistry and Biophysics, 1992
In this work we examine the carbohydrate binding properties of human placental mannose receptor (HMR) using a rapid and sensitive enzyme-linked immunosorbent microplate assay. The assay is based on the inhibition of binding of highly purified receptor to yeast mannan-coated 96-well plates. The specificity of ligand binding was inferred from the potency
V, Kéry, J J, Krepinský, C D, Warren, P, Capek, P D, Stahl   +4 more
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The Macrophage Mannose Receptor: Current Status

American Journal of Respiratory Cell and Molecular Biology, 1990
Sugar-specific recognition of oligosaccharide chains present on macromolecules and particles has emerged as an important mechanism by which macrophages carry out a variety offunctions including host defense, molecular scavenging, and cell-cell recognition.
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Metal ions and human sperm mannose receptors

Andrologia, 2000
Zinc and lead concentrations were measured in seminal plasma from fertile donors, infertile men with varicocoele and men undergoing work-ups for in vitro fertilization. Ejaculated spermatozoa from these subjects were incubated in vitro with various metal ions and/or dibromoethane and dibromochloropropane. Mannose receptor expression was correlated with
S, Benoff, G W, Cooper, G M, Centola, A, Jacob, A, Hershlag, I R, Hurley   +5 more
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Mannose receptor and phagocytosis

1999
Publisher Summary This chapter discusses the role of mannose receptor in phagocytosis. The mannose receptor (MR) is a ≈175 kDa transmembrane receptor expressed on resident macrophage subpopulations, dendritic cells, and on subsets of endothelial cells.
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Macrophage mannose receptor in chronic sinus disease

Allergy, 2004
Background:  The role of infectious agents in the onset and maintenance of chronic sinus disease is still not fully understood. Macrophage mannose receptor (MMR), an innate pattern recognizing receptor, capable of phagocytosis of invaders and signal transduction for proinflammatory mechanisms, might be of importance in immune interactions in chronic ...
S, Claeys, T, De Belder, G, Holtappels, P, Gevaert, B, Verhasselt, P, Van Cauwenberge, C, Bachert   +6 more
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Mannose Receptor and Targeting Strategies

2019
The mannose family receptors are unique multidomain, multifunctional endocytic receptors belonging to the C-type lectin family. These receptors, although structurally similar, exhibit differential binding to discrete ligands. This chapter discusses such similarities and differences between the structures, ligands, the expression, and molecular ...
Priyanka Jahagirdar, Amit S. Lokhande, Prajakta Dandekar, Padma V. Devarajan   +3 more
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The Cation-Dependent Mannose 6-Phosphate Receptor

2001
The 46kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) and the 300kDa cation-independent mannose 6-phosphate receptor (CI-MPR) are the sole members of the P-type family of lectins, which derive their name from their ability to bind phosphorylated mannose residues.
J J, Kim, N M, Dahms
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The Mannose Receptor in the Brain

2003
The mannose receptor is a transmembrane glycoprotein mainly expressed by macrophages, that specifically binds to mannosylated molecules and mediates their endocytosis. Known ligands of the receptor are lysosomases and various pathogens. Ligand specificity and cellular distribution provide the mannose receptor with a very important role in homeostasis ...
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