Hijacking bacterial glycosylation for the production of glycoconjugates, from vaccines to humanised glycoproteins. [PDF]
OBJECTIVES: Glycosylation or the modification of a cellular component with a carbohydrate moiety has been demonstrated in all three domains of life as a basic post-translational process important in a range of biological processes. This review will focus
Aggarwal +65 more
core +1 more source
Lysosomal alpha-mannosidase and alpha-mannosidosis
Lysosomal alpha-mannosidase with acidic pH optimum is ubiquitous in human tissues where is expressed in two major forms, A and B that are the product of a single gene located on chromosome 19. Mutations in the gene encoding for alpha-mannosidase cause alpha- mannosidosis, an autosomal recessive disease, resulting in the accumulation of unprocessed ...
Silvia, Paciotti +8 more
openaire +2 more sources
Distinct CD16a features on human NK cells observed by flow cytometry correlate with increased ADCC
Natural killer (NK) cells destroy tissue that have been opsonized with antibodies. Strategies to generate or identify cells with increased potency are expected to enhance NK cell-based immunotherapies.
Maria C. Rodriguez Benavente +6 more
doaj +1 more source
Forest management affects microbial community composition depending on forest type. Vegetation type has the strongest effect on microbial composition, while management alters community structure without affecting function, highlighting the importance of vegetation in forest soil ecosystem dynamics.
Enrica Picariello, Flavia De Nicola
wiley +1 more source
Análisis proteómico de la expresión de enzimas que degradan lignocelulosa en el secretoma de Penicillium purpurogenum crecido en distintas fuentes de carbono [PDF]
Tesis (Doctor en Biociencias Moleculares)RESUMEN: Penicilliumpurpurogenum es un hongo capaz de crecer en fuentes de carbono provenientes de diversas fuentes vegetales, lo que refleja una gran capacidad de adaptación al medio.
Navarrete Lagos, Mario Augusto
core
ERGIC-53 is a functional mannose-selective and calcium-dependent human homologue of leguminous lectins [PDF]
Based on sequence homologies with leguminous lectins, the intermediate compartment marker ERGIC-53 was proposed to be a member of a putative new class of animal lectins associated with the secretory pathway.
Itin, C. +3 more
core +1 more source
Background Mannans are key components of lignocellulose present in the hemicellulosic fraction of plant primary cell walls. Mannan endo-1,4-β-mannosidases (1,4-β-D-mannanases) catalyze the random hydrolysis of β-1,4-mannosidic linkages in the main chain ...
Sigoillot Jean-Claude +6 more
doaj +1 more source
Quinic Acid and Synthetic Derivatives in Medicinal Chemistry
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel +2 more
wiley +1 more source
Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. [PDF]
Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have shown by N-glycanase digestion that LCMV strain Arm-4 bears five oligosaccharides on GP-1 and ...
Buchmeier, MJ +3 more
core
Mannanase hydrolysis of spruce galactoglucomannan focusing on the influence of acetylation on enzymatic mannan degradation [PDF]
Background: Galactoglucomannan (GGM) is the most abundant hemicellulose in softwood, and consists of a backbone of mannose and glucose units, decorated with galactose and acetyl moieties.
Arnling Bååth, Jenny +5 more
core +1 more source

