Results 61 to 70 of about 4,480 (203)

A Practical and Flexible De Novo Synthesis of Deoxygenated Carbasugars and Their Cyclitol Epoxides

European Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.
A de novo synthesis route comprising enantioselective Brown crotylation and ring‐closing metathesis as the key steps enables the synthesis of a‐ and b‐carba‐paratose, a‐ and b‐carba‐colitose as well as four configurational deoxycyclophellitol isosteres.
Yevhenii Radchenko, Nick D. F. Puijmbroeck, Sanne M. Verduin, Jeroen D. C. Codée, Herman S. Overkleeft   +4 more
wiley   +1 more source

Bacterial Synergism in Lignocellulose Biomass Degradation – Complementary Roles of Degraders As Influenced by Complexity of the Carbon Source

Frontiers in Microbiology, 2017
Lignocellulosic biomass (LCB) is an attractive source of carbon for the production of sugars and other chemicals. Due to its inherent complexity and heterogeneity, efficient biodegradation requires the actions of different types of hydrolytic enzymes. In
Larisa Cortes-Tolalpa, Joana F. Salles, Jan Dirk van Elsas   +2 more
doaj   +1 more source

Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans [PDF]

, 2009
Exposure to sub-lethal levels of stress, or hormesis, was a means to induce longevity. By screening for mutations that enhance resistance to multiple stresses, we identified multiple alleles of alpha-1,2-mannosidase I (mas1) which, in addition to ...
Benzer, Seymour, Brummel, Theodore J., Kao, Tzu-Yu, Li, Fang-Yi, Liao, Pin-Chao, Lin, Pei-Ting, Liu, Ya-Lin, Lu, Wan-Chih, Wang, Horng-Dar, Yuh, Chiou-Hwa   +9 more
core   +1 more source

Quantification of Specific Urinary Oligosaccharide Biomarkers for Diagnosis and Treatment Monitoring of Alpha‐Mannosidosis

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Alpha‐mannosidosis (AM, OMIM# 248500), an ultra‐rare lysosomal storage disorder (LSD), is caused by insufficient activity of alpha‐mannosidase, an enzyme involved in degradation of N‐glycan oligosaccharides. Hence, specific oligosaccharides accumulate in tissues, resulting in a progressive multi‐organ disease.
Dominik Dörfel, Benjamin Dreyer, Mona Lindschau, Antonio Barbato, Nadia Altavilla, Giancarlo la Marca, Lara Maleen Marten, Friederike Bürger, Mara Botti, Lina Verena Sevenich, Ronen Spiegel, Anke Schumann, Melanie Herrmann, Davor Fielitz, Nicole Muschol, René Santer, Simona Murko   +16 more
wiley   +1 more source

Characterization of the  - and  -Mannosidases of Porphyromonas gingivalis [PDF]

Journal of Bacteriology, 2013
Mannose is an important sugar in the biology of the Gram-negative bacterium Porphyromonas gingivalis. It is a major component of the oligosaccharides attached to the Arg-gingipain cysteine proteases, the repeating units of an acidic lipopolysaccharide (A-LPS), and the core regions of both types of LPS produced by the organism (O-LPS and A-LPS) and a ...
Minnie, Rangarajan, Joseph, Aduse-Opoku, Ahmed, Hashim, Nikolay, Paramonov, Michael A, Curtis   +4 more
openaire   +2 more sources

Intracellular activation of rat hepatic lipase requires transport to the Golgi compartment and is associated with a decrease in sedimentation velocity [PDF]

, 2000
Hepatic lipase (HL) is an N-glycoprotein that acquires triglyceridase activity somewhere during maturation and secretion. To determine where and how HL becomes activated, the effect of drugs that interfere with maturation ...
Jansen, H. (Hans), Neve, B.P. (Bernadette), Verhoeven, A.J.M. (Adrie)   +2 more
core   +2 more sources

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

At the nexus of three kingdoms: the genome of the mycorrhizal fungus Gigaspora margarita provides insights into plant, endobacterial and fungal interactions. [PDF]

, 2020
As members of the plant microbiota, arbuscular mycorrhizal fungi (AMF, Glomeromycotina) symbiotically colonize plant roots. AMF also possess their own microbiota, hosting some uncultivable endobacteria.
Amselem, Joëlle, Bonfante, Paola, Ghignone, Stefano, Grigoriev, Igor V, Henrissat, Bernard, Lipzen, Anna, Martin, Francis M, Morin, Emmanuelle, Novero, Mara, Salvioli di Fossalunga, Alessandra, Sędzielewska Toro, Kinga, Venice, Francesco, Xianan, Xie   +12 more
core   +3 more sources

Advances in Wine Yeast Autolysis: Biochemical and Molecular Mechanisms, and the Release of Organic Compounds in White and Sparkling Wines—An Updated Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Wine yeasts play a central role in alcoholic fermentation and significantly contribute to the sensory attributes of wines through cellular autolysis during lees aging (sur lie), especially in white wines. This process releases organic compounds that alter the wine's chemical and sensory profile.
José Ricardo Machado dos Santos, Aniela Pinto Kempka   +1 more
wiley   +1 more source

A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation [PDF]

, 2016
Glycosylation greatly influences the safety and efficacy of many of the highest-selling recombinant therapeutic proteins (rTPs). In order to define optimal cell culture feeding strategies that control rTP glycosylation, it is necessary to know how ...
Jimenez del Val, I, Kontoravdi, C, Polizzi, K   +2 more
core   +1 more source