Results 1 to 10 of about 13,659,719 (307)

Heritability Enrichment of Immunoglobulin G N-Glycosylation in Specific Tissues [PDF]

Frontiers in Immunology, 2021
Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with immunoglobulin G (IgG) N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain.
Xingang Li, Xingang Li, Hao Wang, Hao Wang, Yahong Zhu, Weijie Cao, Weijie Cao, Manshu Song, Manshu Song, Youxin Wang, Haifeng Hou, Minglin Lang, Xiuhua Guo, Xuerui Tan, Jingdong J. Han, Wei Wang, Wei Wang, Wei Wang, Wei Wang, Wei Wang   +19 more
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N-linked glycosylation enzymes in the diatom Thalassiosira oceanica exhibit a diel cycle in transcript abundance and favor for NXT-type sites

Scientific Reports, 2021
N-linked glycosylation is a posttranslational modification affecting protein folding and function. The N-linked glycosylation pathway in algae is poorly characterized, and further knowledge is needed to understand the cell biology of algae and the ...
Joerg Behnke, Alejandro M. Cohen, Julie LaRoche   +2 more
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Allergy Associated With N-glycans on Glycoprotein Allergens

Shengwu huaxue yu shengwu wuli jinzhan
Protein as the allergens could lead to allergy. In addition, a widespread class of allergens were known as glycans of N-glycoprotein. N-glycoprotein contained oligosaccharide linked by covalent bonds with protein. Recently,studies implicated that allergy
ZHANG Yu-Xin, LIU Rui-Jie, ZHANG Shao-Xing, YUAN Shu-Ying, CHEN Yan-Wen, YE Yi-Lin, LIN Qian-Ge, LU Xin-Rong, TONG Yong-Liang, CHEN Li, SUN Gui-Qin   +10 more
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Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins

Scientific Reports, 2021
Here, we present for the first time, a site-specific N-glycosylation analysis of proteins from a Brazilian Zika virus (ZIKV) strain. The virus was propagated with high yield in an embryo-derived stem cell line (EB66, Valneva SE), and concentrated by g ...
Alexander Pralow, Alexander Nikolay, Arnaud Leon, Yvonne Genzel, Erdmann Rapp, Udo Reichl   +5 more
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N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer

Cell Death and Disease, 2023
KIAA1324 is a transmembrane protein largely reported as a tumor suppressor and favorable prognosis marker in various cancers, including gastric cancer.
Rebecca Yun, Eunji Hong, Junil Kim, Bora Park, Staci Jakyong Kim, Bona Lee, Yong Sang Song, Seong-Jin Kim, Sujin Park, Jin Muk Kang   +9 more
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Identifying Components of a Halobacterium salinarum N-Glycosylation Pathway

Frontiers in Microbiology, 2021
Whereas N-glycosylation is a seemingly universal process in Archaea, pathways of N-glycosylation have only been experimentally verified in a mere handful of species.
Zlata Vershinin, Marianna Zaretsky, Ziqiang Guan, Jerry Eichler   +3 more
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An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma

Journal of Translational Medicine, 2022
Background Aberrant glycosylation has been recognized as a hallmark of cancer and N-glycosylation is one of the main types of glycosylation in eukaryotes.
Yingzhen Gao, Liuyi Shen, Tianyue Dong, Xin Yang, Heyang Cui, Yanlin Guo, Yanchun Ma, Pengzhou Kong, Xiaolong Cheng, Ling Zhang, Yongping Cui   +10 more
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STT3B promotes porcine epidemic diarrhea virus replication by regulating N-glycosylation of PEDV S protein

Journal of Virology
Porcine epidemic diarrhea virus (PEDV), a highly pathogenic enteric coronavirus, has caused significant economic losses worldwide in recent years.
Huixin Zhu, Jinxiu Lou, Zhen Yang, Juan Bai, Ping Jiang, Xianwei Wang, Xing Liu   +6 more
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The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosis

Journal of Biomedical Science, 2020
N-linked glycosylation is one of the most abundant posttranslational modifications of membrane-bound proteins in eukaryotes and affects a number of biological activities, including protein biosynthesis, protein stability, intracellular trafficking ...
Ying-Nai Wang, Heng-Huan Lee, Jennifer L. Hsu, Dihua Yu, Mien-Chie Hung   +4 more
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Similarities and Differences in the Glycosylation Mechanisms in Prokaryotes and Eukaryotes

International Journal of Microbiology, 2010
Recent years have witnessed a rapid growth in the number and diversity of prokaryotic proteins shown to carry N- and/or O-glycans, with protein glycosylation now considered as fundamental to the biology of these organisms as it is in eukaryotic systems ...
Anne Dell, Alaa Galadari, Federico Sastre, Paul Hitchen   +3 more
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