Results 41 to 50 of about 182,092 (302)

A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member [PDF]

, 2005
Pleurotus ostreatus produces several extracellular proteases which are believed to be involved in the regulation of the ligninolytic activities of this fungus. Recently, purification and characterization of the most abundant P.
FARACO, VINCENZA, FESTA, GIOVANNA, GIARDINA, PAOLA, MONTI, MARIA, PALMIERI G., SANNIA, GIOVANNI   +5 more
core   +2 more sources

Unraveling the Mechanism of Protein N-Glycosylation [PDF]

Journal of Biological Chemistry, 2005
Asparagine-linked glycosylation is the most ubiquitous protein co-translational modification in the endoplasmic reticulum (ER). The enzyme that catalyzes this process is called oligosaccharyl transferase (OT). It catalyzes the transfer of an oligosaccharyl moiety (Glc3Man9GlcNAc2) from the dolichol-linked pyrophosphate donor to the side chain of Asn ...
Lennarz, WJ, Yan, A
openaire   +4 more sources

Changes in protein N-glycosylation during the fruit development and ripening in melting-type peach

Food Materials Research, 2021
The posttranslational modification of proteins with complex carbohydrate moieties (glycosylation) regulates the process of fruit ripening. Exoglycosidases are enzymes that can trim this protein glycosylation and are therefore considered to be important ...
Ting Wang, Xi-Ran Jia, Li Liu, Josef Voglmeir   +3 more
doaj   +1 more source

N-linked glycosylation enzymes in the diatom Thalassiosira oceanica exhibit a diel cycle in transcript abundance and favor for NXT-type sites

Scientific Reports, 2021
N-linked glycosylation is a posttranslational modification affecting protein folding and function. The N-linked glycosylation pathway in algae is poorly characterized, and further knowledge is needed to understand the cell biology of algae and the ...
Joerg Behnke, Alejandro M. Cohen, Julie LaRoche   +2 more
doaj   +1 more source

N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer

Cell Death and Disease, 2023
KIAA1324 is a transmembrane protein largely reported as a tumor suppressor and favorable prognosis marker in various cancers, including gastric cancer.
Rebecca Yun, Eunji Hong, Junil Kim, Bora Park, Staci Jakyong Kim, Bona Lee, Yong Sang Song, Seong-Jin Kim, Sujin Park, Jin Muk Kang   +9 more
doaj   +1 more source

Posttranslational modifications of GLUT4 affect its subcellular localization and translocation [PDF]

, 2013
The facilitative glucose transporter type 4 (GLUT4) is expressed in adipose and muscle and plays a vital role in whole body glucose homeostasis. In the absence of insulin, only ~1% of cellular GLUT4 is present at the plasma membrane, with the vast ...
Bayer, Begum, Birnbaum, Bogan, Bogan, Bogan, Bryant, Cassie Welburn, Chang, Fujita, Garvey, Gill, Giorgino, Govers, Grasbon-Frodl, Gwyn Gould, Haga, Hardy, Herrmann, Hicke, Huang, Ing, James, James, Jessica Sadler, Jeyaraj, Karylowski, Kupriyanova, Lamb, Lau, Lawrence, Lawrence, Leto, Li, Liu, Livingstone, Mahajan, Marsh, Marshall, Marshall, Martin, Matunis, McCormick, Muller, Nia Bryant, Perera, Pessin, Pilch, Piper, Ren, Reusch, Saltiel, Semiz, Shi, Shi, Stöckli, Toh, Urbe, Vannucci, Varki, Watson, Williams, Yang, Yu, Zaarour   +64 more
core   +3 more sources

Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]

, 2014
The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb) capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment which will be too expensive to be accessible by the most ...
EMEA, Montefiori D.C., Pabst M., Pegu A., WHO   +4 more
core   +1 more source

Enhancement of toxin- and virus-neutralizing capacity of single-domain antibody fragments by -glycosylation [PDF]

, 2009
Single-domain antibody fragments (VHHs) have several beneficial properties as compared to conventional antibody fragments. However, their small size complicates their toxin- and virus-neutralizing capacity.
M. M. Harmsen, C. B. van Solt, H. P. D. Fijten, FM Apter, P Cuatrecasas, LGJ Frenken, Y Gavel, C Hamers-Casterman, SR Hamilton, MM Harmsen, MM Harmsen, MM Harmsen, MM Harmsen, MM Harmsen, MM Harmsen, J Holmgren, MA Kukuruzinska, MP Lefranc, MG Mateu, J McCafferty, S Muyldermans, PW Parren, D Saerens, CM Sagt, AM Sinclair, TK Sixma, BD Spangler, JI Speirs, R Strasser, RH Van der Linden, JM Van der Vaart, A Wright   +31 more
core   +2 more sources

Increased efficiency of Campylobacter jejuni N-oligosaccharyltransferase PglB by structure-guided engineering [PDF]

Open Biology, 2015
Conjugate vaccines belong to the most efficient preventive measures against life-threatening bacterial infections. Functional expression of N-oligosaccharyltransferase (N-OST) PglB of Campylobacter jejuni in Escherichia coli enables a simplified ...
Julian Ihssen, Jürgen Haas, Michael Kowarik, Luzia Wiesli, Michael Wacker, Torsten Schwede, Linda Thöny-Meyer   +6 more
doaj   +1 more source

Role of N-glycosylation in oral cancer [PDF]

, 2017
Oral squamous cell carcinoma represents more than 90% head and neck cancers with high incidence rate and morbidity. To date, little is known about the molecular mechanisms responsible for OSCC initiation and progression to advanced disease.
Bukhari, Samah
core