Results 61 to 70 of about 13,659,719 (307)
Glycosylation pathways are mediated by N-glycosylation.
, 2020 (A) N-glycan biosynthesis and (B) GPI anchor biosynthesis. (C) Changes in N-glycosylation protein levels in three glycosylation pathways at different stages. N-glycosylated proteins were marked in red font; N-glycosite was indicated by red ring.
Zhiyong Ren (2017543) +5 more
core +1 more source
Quantitative Analyses Reveal Novel Roles for
mBio, 2019 In eukaryotes, glycosylation plays a role in proteome stability, protein quality control, and modulating protein function; however, similar studies in bacteria are lacking.
Sherif Abouelhadid +8 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Label-Free Quantitative Comparison of N-Glycoproteomics between Camel and Cow Milk [PDF]
Shipin KexueTo understand the differential N-glycoprotein characteristics of camel versus cow milk, we employed label-free quantitative N-glycoproteomics to compare the N-glycoprotein composition and the number of N-glycosylation sites between the two milks and ...
LI Danlei, KONG Xiabing, YU Yue, HU Qian, ZHANG Jiukai, CHEN Ying
doaj +1 more source
Defects in N‐glycosylation induce apoptosis in yeast [PDF]
Molecular Microbiology, 2005 SummaryN‐glycosylation in the endoplasmic reticulum is an essential protein modification and highly conserved in evolution from yeast to man. Defects of N‐glycosylation in humans lead to congenital disorders. The pivotal step of this pathway is the transfer of the evolutionarily conserved lipid‐linked core‐oligosaccharide to the nascent polypeptide ...
Peter, Hauptmann +5 more
openaire +2 more sources
Table_1_Heritability Enrichment of Immunoglobulin G N-Glycosylation in Specific Tissues.xlsx
, 2021 Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with immunoglobulin G (IgG) N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain.
Yahong Zhu (10931715) +11 more
core +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
N-glycosylation in Haloferax volcanii: adjusting the sweetness [PDF]
Frontiers in Microbiology, 2013 Long believed to be restricted to Eukarya, it is now known that cells of all three domains of life perform N-glycosylation, the covalent attachment of glycans to select target protein asparagine residues. Still, it is only in the last decade that pathways of N-glycosylation in Archaea have been delineated.
Eichler, Jerry +5 more
openaire +3 more sources