Modeling Congenital Disorders of N-Linked Glycoprotein Glycosylation in Drosophila melanogaster [PDF]
Frontiers in Genetics, 2018 Protein glycosylation, the enzymatic addition of N-linked or O-linked glycans to proteins, serves crucial functions in animal cells and requires the action of glycosyltransferases, glycosidases and nucleotide-sugar transporters, localized in the ...
Anna Frappaolo +6 more
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Proteome-wide analysis of single-nucleotide variations in the N-glycosylation sequon of human genes. [PDF]
PLoS ONE, 2012 N-linked glycosylation is one of the most frequent post-translational modifications of proteins with a profound impact on their biological function.
Raja Mazumder +4 more
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Journal of Integrative Agriculture, 2019 N-Linked glycosylation of hemagglutinin (HA) has been demonstrated to regulate the virulence and receptor-binding specificity of avian influenza virus (AIV).
Liu-gang TAN +8 more
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Identifying Components of a Halobacterium salinarum N-Glycosylation Pathway
Frontiers in Microbiology, 2021 Whereas N-glycosylation is a seemingly universal process in Archaea, pathways of N-glycosylation have only been experimentally verified in a mere handful of species.
Zlata Vershinin +3 more
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N-Linked Glycosylation Regulates CD22 Organization and Function
Frontiers in Immunology, 2019 The organization and clustering of cell surface proteins plays a critical role in controlling receptor signaling; however, the biophysical mechanisms regulating these parameters are not well understood.
Laabiah Wasim +11 more
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Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose Condition. [PDF]
PLoS ONE, 2016 ATP-binding cassette C11 (ABCC11) is a plasma membrane protein involved in the transport of a variety of lipophilic anions. ABCC11 wild-type is responsible for the high-secretion phenotypes in human apocrine glands, such as that of wet-type ear wax, and ...
Yu Toyoda +4 more
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Biological Functions of Glycosylation and Their Application in Glycoengineered Therapeutics
ChemEngineeringGlycosylation is the most common post-translational modification in the human proteome, with over half of all human proteins bearing covalently attached glycans.
Corbyn Kubalek +7 more
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Effects of exercise on the hexosamine biosynthetic pathway and glycosylation
Journal of Physical Fitness and Sports Medicine, 2012 Minor amounts of glucose incorporated into the cells is metabolized via the hexosamine biosynthetic pathway, resulting in the production of uridine-5’-diphosphate-N-acetylglucosamine (UDP-GlcNAc), which is utilized as a donor substrate for the N- and O ...
Ken Shirato +3 more
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Characterisation of N-linked protein glycosylation in the bacterial pathogen Campylobacter hepaticus
Scientific Reports, 2023 Campylobacter hepaticus is an important pathogen which causes Spotty Liver Disease (SLD) in layer chickens. SLD results in an increase in mortality and a significant decrease in egg production and therefore is an important economic concern of the global ...
Jamieson B. McDonald +5 more
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Frontiers in Cell and Developmental Biology, 2022 Glycosylation is a ubiquitous and universal cellular process in all domains of life. In eukaryotes, many glycosylation pathways occur simultaneously onto proteins and lipids for generating a complex diversity of glycan structures.
Zoé Durin +7 more
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