Results 81 to 90 of about 13,659,719 (307)
Synthetic strategies toward 1,3-oxathiolane nucleoside analogues
Beilstein Journal of Organic Chemistry, 2021 Sugar-modified nucleosides have gained considerable attention in the scientific community, either for use as molecular probes or as therapeutic agents. When the methylene group of the ribose ring is replaced with a sulfur atom at the 3’-position, these ...
Umesh P. Aher +3 more
doaj +1 more source
World Journal of Advanced Research and ReviewsMaillard reaction includes interaction of reducing sugar with any compound containing free amino group, which is resulted in formation of colored high-molecular compounds [1, 2]. Despite intensive research, a complete mechanism of Maillard reaction is still undefined.
Karkashadze, Nino Guram +6 more
openaire +2 more sources
GlycoVis: Visualizing Glycan Distribution in the Protein N-Glycosylation Pathwayin Mammalian Cells
, 2016 Glycosylation pattern is an important quality attribute of protein therapeutics. It affects protein stability, half-life and even biological functions. The N-glycosylation pathway is a highly branched network.
Hossler, Patrick, Hu, Wei-Shou
core +1 more source
DataSheet_1_Heritability Enrichment of Immunoglobulin G N-Glycosylation in Specific Tissues.docx
, 2021 Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with immunoglobulin G (IgG) N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain.
Yahong Zhu (10931715) +11 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Open Life Sciences, 2023 The Dolichol kinase (DOLK) gene encodes the polytopic DOLK protein associated with the endoplasmic reticulum (ER) N-glycosylation pathway catalyzing the final step in the biosynthesis of dolichol phosphate.
Farooqi Nadia +8 more
doaj +1 more source
Table_8_Heritability Enrichment of Immunoglobulin G N-Glycosylation in Specific Tissues.xlsx
, 2021 Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with immunoglobulin G (IgG) N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain.
Yahong Zhu (10931715) +11 more
core +1 more source
Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez +5 more
wiley +1 more source
Congenital protein hypoglycosylation diseases
The Application of Clinical Genetics, 2012 Susan E SparksDepartment of Pediatrics, Levine Children's Hospital at Carolinas Medical Center, Charlotte, NC, USA; Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC, USAAbstract: Glycosylation is an ...
Sparks SE
doaj
N-glycosylation observed in crystal structures of asco-laccases.
, 2018 N-glycosylation observed in crystal structures of asco-laccases.
Morten J. Bjerrum (1441012) +7 more
core +1 more source