Results 11 to 20 of about 182,092 (302)
Studying Lactoferrin N-Glycosylation. [PDF]
International Journal of Molecular Sciences, 2017 Lactoferrin is a multifunctional glycoprotein found in the milk of most mammals. In addition to its well-known role of binding iron, lactoferrin carries many important biological functions, including the promotion of cell proliferation and ...
Barile, Daniela +4 more
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Genetics and Molecular Biology, 2001 The N-linked glycosylation of secretory and membrane proteins is the most complex posttranslational modification known to occur in eukaryotic cells. It has been shown to play critical roles in modulating protein function.
Maia Ivan G., Leite Adilson
doaj +5 more sources
, 2016 The present invention relates to a mammalian cell comprising a gene encoding a polypeptide of interest, wherein the polypeptide of interest is expressed comprising one or more posttranslational modification patterns. These modifications are useful for example in glycoprotein production where the antibodies with the modifications have an enhanced ...
Behrens, Carsten +6 more
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Platelets and Defective N-Glycosylation [PDF]
International Journal of Molecular Sciences, 2020 N-glycans are covalently linked to an asparagine residue in a simple acceptor sequence of proteins, called a sequon. This modification is important for protein folding, enhancing thermodynamic stability, and decreasing abnormal protein aggregation within the endoplasmic reticulum (ER), for the lifetime and for the subcellular localization of proteins ...
Mammadova-Bach, Elmina +3 more
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Human plasma protein N-glycosylation [PDF]
Glycoconjugate Journal, 2015 Glycosylation is the most abundant and complex protein modification, and can have a profound structural and functional effect on the conjugate. The oligosaccharide fraction is recognized to be involved in multiple biological processes, and to affect proteins physical properties, and has consequentially been labeled a critical quality attribute of ...
Clerc, F. +5 more
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Stereoselective N-Glycosylation by Staudinger Ligation [PDF]
Organic Letters, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Yi, He +3 more
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Diagnostic accuracy of urinary prostate protein glycosylation profiling in prostatitis diagnosis [PDF]
, 2015 Introduction: Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in
Decaestecker, Karel +8 more
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Proteome-wide analysis of single-nucleotide variations in the N-glycosylation sequon of human genes. [PDF]
PLoS ONE, 2012 N-linked glycosylation is one of the most frequent post-translational modifications of proteins with a profound impact on their biological function.
Raja Mazumder +4 more
doaj +1 more source
The impact of elevation of total bilirubin level and etiology of the liver disease on serum N-glycosylation patterns in mice and men [PDF]
, 2010 The GlycoFibroTest and GlycoCirrhoTest are noninvasive alternatives for liver biopsy that can be used as a follow-up tool for fibrosis patients and to diagnose cirrhotic patients, respectively.
BLOMME, BRAM +5 more
core +1 more source
Serum Protein N-Glycosylation Signatures of Neuroblastoma [PDF]
Frontiers in Oncology, 2021 BackgroundNeuroblastoma is the most common extracranial childhood solid tumor which accounts for 10% of the malignancies and 15% of the cancer fatalities in children. N-glycosylation is one of the most frequent post-translation protein modification playing a vital role in numerous cancers. N-glycosylation changes in neuroblastoma patient serum have not
Wenjun Qin +5 more
openaire +3 more sources