Results 71 to 80 of about 36,569 (192)

Rutaecarpine Improves Hyperlipidemia‐Related Erectile Dysfunction in Rats by Inhibiting Macrophage M1 Polarization‐Induced Corpus Cavernosum Fibrosis

Andrology, EarlyView.
ABSTRACT Background Hyperlipidemia‐related erectile dysfunction (HLED) responds poorly to first‐line treatments such as phosphodiesterase type 5 inhibitors (PDE5Is), emphasizing the need for alternative therapeutic strategies. Rutaecarpine (RUT), a bioactive alkaloid, exhibits significant anti‐inflammatory and anti‐fibrotic effects.
Bocheng Tu, Shiqing Zhu, Peng Hu, Xiaoyu Zhu, Jiaxin Wang, Xinqi Liu, Sen Fu, Tao Wang, Jihong Liu, Kai Cui   +9 more
wiley   +1 more source

High-resolution manometry is superior to endoscopy and radiology in assessing and grading sliding hiatal hernia: A comparison with surgical in vivo evaluation

United European Gastroenterology journal, 2018
Background Hiatal hernia is diagnosed by barium-swallow esophagogram or esophagogastroduodenoscopy, with possible suboptimal results. High-resolution manometry clearly identifies crural diaphragm and lower esophageal sphincter.
S. Tolone, E. Savarino, G. Zaninotto, C. Gyawali, M. Frazzoni, N. de Bortoli, L. Frazzoni, G. del Genio, G. Bodini, M. Furnari, V. Savarino, L. Docimo   +11 more
semanticscholar   +1 more source

Value of 3D‐High Resolution Anorectal Manometry Before and After Fistulotomy for Simple Perianal Fistulas: A Prospective Cohort Study

ANZ Journal of Surgery, EarlyView.
In this prospective cohort study, 3D‐high resolution anorectal manometry provided detailed regional pressure assessment but failed to predict postoperative continence deterioration after fistulotomy for simple perianal fistulas. These findings highlight the need for a continence assessment tool that better distinguishes true fecal incontinence from ...
Justin Y. van Oostendorp, Pieter van Hagen, Ruben Veldkamp, Lisette Dekker, Ingrid J. M. Han‐Geurts   +4 more
wiley   +1 more source

Association of Mean Nocturnal Baseline Impedance and AFS EGJ Grading With AET‐Defined Reflux Burden in Korean Patients

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Diagnosing gastroesophageal reflux disease (GERD) is challenging in borderline acid exposure time (AET). The Lyon Consensus 2.0 defines AET ≥ 6% as pathological reflux; however, East Asian standards often apply a 4% threshold, creating a diagnostic gray zone.
Ye‐Rin Chae, Ga Hee Kim, Ji Soo Moon, Jin Won Chang, Ji Hoon Yoon, Da Hyun Jung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee   +9 more
wiley   +1 more source

Endoscopic Pseudo‐dilation of Esophagogastric Junction During Peroral Endoscopic Myotomy: (With Video)

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aim During peroral endoscopic myotomy (POEM) for achalasia, endoscopic esophagogastric junction (EGJ) opening is generally considered a sign of successful myotomy. However, in clinical practice, the EGJ may appear to open immediately after submucosal tunneling, even before myotomy is performed.
Kei Ushikubo, Haruhiro Inoue, Ippei Tanaka, Nikko Raymundo, Kazuki Yamamoto, Yuta Tamaru, Kohei Shigeta, Satoshi Abiko, Yohei Nishikawa, Mayo Tanabe, Manabu Onimaru, Koji Otuka, Takayoshi Ito, Noboru Yokoyama   +13 more
wiley   +1 more source

A Review of Making the Modern Diagnosis of Gastrointestinal Reflux Disease: the Lyon Consensus

The Korean Journal of Gastroenterology, 2019
Gastroesophageal reflux disease (GERD) is diagnosed according to the medical history or in response to proton pump inhibitor therapy. However, the need for further testing is always appropriate.
Tae-oh Kim, Hye-Kyung Jung
doaj   +1 more source

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source

Esophageal motility after laparoscopic sleeve gastrectomy

Clinical and Experimental Gastroenterology, 2017
Eleni Sioka,1 George Tzovaras,1 Fotios Tsiopoulos,2 Dimitris Papamargaritis,1 Spyros Potamianos,2 Constantine Chatzitheofilou,1 Dimitris Zacharoulis1 1Department of Surgery, 2Department of Gastroenterology, University Hospital of Larissa, University of ...
Sioka E, Tzovaras G, Tsiopoulos F, Papamargaritis D, Potamianos S, Chatzitheofilou C, Zacharoulis D   +6 more
doaj  

An ANMS-NASPGHAN consensus document on esophageal and antroduodenal manometry in children

Neurogastroenterology and Motility, 2017
Upper gastrointestinal symptoms in children are common and motility disorders are considered in the differential diagnosis. High resolution esophageal manometry (HRM) has revolutionized the study of esophageal physiology, and the addition of impedance ...
R. Rosen, J. Garza, N. Tipnis, S. Nurko
semanticscholar   +1 more source

Clinical Utility of Anti‐reflux Mucosal Intervention for Refractory Gastroesophageal Reflux Disease in Patients With a Hiatal Hernia

DEN Open, Volume 7, Issue 1, April 2027.
Abstract Background Surgical fundoplication is the standard treatment for refractory gastroesophageal reflux disease (GERD) with large (≥3 cm) hiatal hernias; however, its invasiveness is problematic in older adults and high‐risk patients. Anti‐reflux mucosal intervention (ARMI) is a less invasive endoscopic alternative; however, patients with large ...
Masachika Saino, Haruhiro Inoue, Kei Ushikubo, Miyuki Iwasaki, Kazuki Yamamoto, Yohei Nishikawa, Ippei Tanaka, Hidenori Tanaka, Mayo Tanabe, Satoshi Abiko, Boldbaatar Gantuya, Manabu Onimaru, Shiro Oka   +12 more
wiley   +1 more source