Results 61 to 70 of about 141,172 (269)
A seismological study of the mantle beneath Iceland [PDF]
, 2000 Iceland has long been thought to be underlain by a thermal upwelling, or plume, rising from deep within the mantle. This study tests this hypothesis, by a) seeking evidence for a plume in the lower mantle in azimuth anomalies at the NORSAR array and b ...
Pritchard, Matthew James +1 more
core
Arthritis &Rheumatology, EarlyView.Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia +16 more
wiley +1 more source
P-Wave Arrival-Time Tomography of the Middle East Using ISC-EHB and Waveform Data
SeismicaHigh-resolution seismic images are essential to gain insights into tectonic and geodynamical processes and assess seismic hazards. We constructed a P-wave model, MEPT (Middle East P-wave Travel-time), of the upper mantle beneath the Middle East and the ...
Ebru Bozdağ +8 more
doaj +1 more source
Mantle pseudo-isochrons revisited
The 2.0 Ga pseudo-isochron age inferred from the mid-ocean ridge basalt 207Pb/204Pb against 206Pb/204Pb diagram is reexamined on the basis of a statistical box model of mantle processes.
Rudge, J. F.
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Carbon Energy, EarlyView.Heterostructured interfaces can accelerate hydrogen evolution by improving water dissociation, yet their underlying mechanisms remain unclear. This study combines in situ Raman spectroscopy and density functional theory to reveal how the RuO2/TiO2 interface promotes both water dissociation and hydrogen adsorption, providing new insights into the ...
Dwi Sakti Aldianto Pratama +3 more
wiley +1 more source
Three‐dimensional flow in the subslab mantle
Geochemistry, Geophysics, Geosystems, 2014 Three‐dimensional models of mantle flow at subduction zones make it possible to explain the common occurrence of trench‐parallel subslab seismic anisotropy.
Karen Paczkowski +3 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
Frontiers in Marine Science, 2019 The proteins derived from the foliated shell layer of the oyster, Crassostrea virginica, are unusually acidic and highly phosphorylated. Here we report the identification of a gene encoding a member of this class of phosphoproteins that we collectively ...
Mary Beth Johnstone +5 more
doaj +1 more source