Results 71 to 80 of about 58,594 (258)

Melting of CaSiO3 Perovskite at High Pressure

open access: yesGeophysical Research Letters, 2019
Ab initio molecular dynamics simulations predict that CaSiO3 perovskite melts at 5600 K at 136 GPa, and 6400 K at 300 GPa, significantly higher than MgSiO3 perovskite. The entropy of melting (1.8 kB per atom) is much larger than that of many silicates at
James Braithwaite, Lars Stixrude
doaj   +1 more source

Design and implementation of a 3D‐printed modular distillation tower for experimental teaching in chemical engineering

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Several authors have reported the disconnection between the skills, abilities, and attitudes of graduates from STEM careers with the current needs of the labour market. In science and engineering fields, research has found the need for interdisciplinary approaches that encourage meaningful learning.
Úrsula Manríquez‐Tolsá   +7 more
wiley   +1 more source

Model‐Based Analysis with Mechanistic Insights to CAR‐T‐Cell Therapy Kinetics: Case Study with Axicabtagene Ciloleucel and Brexucabtagene Autoleucel

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Model‐informed drug development is increasingly used to support chimeric antigen receptor (CAR)‐T‐cell therapy programs. However, most population pharmacokinetic (PK) CAR‐T‐cell models available in literature are variations of an empirical piecewise‐linear model, which accurately describes the observed data but lacks a mechanistic foundation.
Anna M. Mc Laughlin   +4 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Research progress and current status of dynamic wave propagation characteristics in rock mass: A review

open access: yesDeep Underground Science and Engineering, EarlyView.
This review elucidates the velocity–dispersion–attenuation coupling mechanisms of wave propagation in rock masses, compares six representative models, and reveals how pressure, temperature, mineral composition, and anisotropy jointly control dynamic responses in complex geological media.
Jiajun Shu   +8 more
wiley   +1 more source

Editorial: Water in the Earth’s interior

open access: yesFrontiers in Earth Science, 2022
Hongzhan Fei   +3 more
doaj   +1 more source

Dietary partitioning mediates species coexistence in the high seas area of northwest Pacific

open access: yesEcography, EarlyView.
Niche partitioning, manifesting along various axes of the ecological niche, is a fundamental mechanism mediating species coexistence in a system. However, the emergence of many species in marine ecosystems would face considerable constraints in achieving coexistence through spatiotemporal differentiation mechanisms under the framework of niche ...
Na Zang   +6 more
wiley   +1 more source

Global threats, local opportunities: ice‐related landforms provide refugia for high‐elevation plants and arthropods

open access: yesEcography, EarlyView.
Ice‐related landforms in mountain areas have been hypothesized to play a key role in the survival of cold‐adapted species threatened by climate change. However, our understanding of such landforms acting as refugia remains speculative. Here we analyse occurrence data, collected through a standardized sampling at 471 sampling points across the European ...
Mauro Gobbi   +4 more
wiley   +1 more source

Fluorinated and B‐Vinylated Tris(pyridyl)borate in Copper(I) Coordination Chemistry

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
Coordinatively flexible tris(pyridyl)borate stabilizes copper coordination complexes, including those with ethylene and carbon monoxide. Fluorinated tris(pyridyl)borate with a vinyl substituent on boron was synthesized and comprehensively characterized, expanding the diversity and functional versatility of the poly(pyridyl)borate ligand family.
Deepika V. Karade   +3 more
wiley   +1 more source

P-Wave Arrival-Time Tomography of the Middle East Using ISC-EHB and Waveform Data

open access: yesSeismica
High-resolution seismic images are essential to gain insights into tectonic and geodynamical processes and assess seismic hazards. We constructed a P-wave model, MEPT (Middle East P-wave Travel-time), of the upper mantle beneath the Middle East and the ...
Ebru Bozdağ   +8 more
doaj   +1 more source

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