Results 141 to 150 of about 27,280 (282)

Scaffold‐free three‐dimensional culture of chronic lymphocytic leukaemia preserves B–T‐cell cross‐talk and enables drug response profiling

British Journal of Haematology, EarlyView.
Summary Chronic lymphocytic leukaemia (CLL) presents a complex biological and clinical landscape, strongly influenced by the tumour microenvironment (TME). To better capture this heterogeneity, we have developed patient‐derived lymphoma spheroids from CLL samples (CLL‐PDLS), which recapitulate the cross‐talk between malignant cells and the autologous ...
Heribert Playa‐Albinyana, Ariadna Giró, Juan A. Piñeyroa, Ferran Araujo‐Ayala, Cèlia Dobaño‐López, Sara Otín‐Sánchez, Elías Campo, Christine Bezombes, Patricia Pérez‐Galán, Dolors Colomer   +9 more
wiley   +1 more source

Identifying the pre‐Odra river system with hydroacoustic and seismic reflection imagery offshore Rügen Island, southern Baltic Sea

Boreas, EarlyView.
Understanding the course and dynamics of ancient river systems, such as the pre‐Odra, provides valuable insights into the post‐glacial evolution of landscapes and riverine processes. The northwest‐trending pre‐Odra was an important drainage system of the European mainland into the Baltic Basin during and after the Scandinavian Ice Sheet retreat ...
Maryse C. Schmidt, Elisabeth Seidel, Christian Hübscher, Benedikt Haimerl, Jonas Preine   +4 more
wiley   +1 more source

The Role of Slab Remnants in Modulating Free Subduction Dynamics: A 3‐D Spherical Numerical Study

Geochemistry, Geophysics, Geosystems
Seismic tomography of Earth's mantle images abundant slab remnants, often located in close proximity to active subduction systems. The impact of such remnants on the dynamics of subduction remains underexplored. Here, we use simulations of multi‐material
Fangqin Chen, D. Rhodri Davies, Saskia Goes, Lior Suchoy, Stephan C. Kramer   +4 more
doaj   +1 more source

Effects of Body Size and Environmental Region on the Nutritional Value of Small Pelagic Species in the California Current

Fisheries Oceanography, EarlyView.
ABSTRACT We evaluated the effects of regional environment and body size on the nutritional traits of five small pelagic species differing in habitat use, feeding behavior, and importance as prey for top predators in the California Current Large Marine Ecosystem (CCLME).
Alana M. Krug‐MacLeod, Miram R. Gleiber, Elan J. Portner, C. Anela Choy, Elizabeth A. Daly, Natasha A. Hardy, Larry B. Crowder, Stephanie J. Green   +7 more
wiley   +1 more source

Influence of Farallon Slab Loading on Intraplate Stress and Seismicity in Eastern North America in the Presence of Pre‐Existing Weak Zones

Geochemistry, Geophysics, Geosystems
Despite the stability of the continental interior, eastern North America has hosted many significant historical earthquakes. Seismicity concentrates within tectonically inherited structures, which can act as weak zones where stress accumulates.
Erin Hightower, Michael Gurnis, Wei Mao
doaj   +1 more source

Petrological features of Subei Basin (Eastern China) lithospheric mantle and their relationships with H2O contents in NAMs

, 2010
The Subei basin is located east of the Tanlu fault, a major discontinuity which separates the Archean North China Craton from the Proterozoic Yangtze Craton.
Hao, Yantao
core  

Resolving Micrometre‐Scale Zircon Growth in Silicic Systems by 7 μm LA‐MC‐ICP‐MS U‐Pb Dating: Linking Petrology and Geochronology in Silicic Volcanic and Granitic Rocks from Victoria, Australia

Geostandards and Geoanalytical Research, EarlyView.
Key Points 7 μm spot‐diameter LA‐MC‐ICP‐MS analyses yield accurate zircon U‐Pb ages. 1013 Ω amplifier resistors improve low‐signal Pb measurements. Saturn correction protocols minimise down‐hole fractionation effects. We present a systematic evaluation of high spatial‐resolution zircon U‐Pb dating using a Thermo Scientific Neoma multi‐collector ICP‐MS ...
Cristiano Lana, John D. Clemens
wiley   +1 more source

Mantle strength of the San Andreas fault system and the role of mantle-crust feedbacks [PDF]

, 2015
In lithospheric-scale strike-slip fault zones, upper crustal strength is well constrained from borehole observations and fault rock deformation experiments, but mantle strength is less well known. Using peridotite xenoliths, we show that the upper mantle
Drury, M.R., Tikoff, B., Chatzaras, V., Newman, J., Withers, A.C.   +4 more
core  

Simulating the Impacts of Deep Geothermal Development on Shallow Hydrothermal Resources in a Rocky Mountain Rift Valley

Groundwater, EarlyView.
Abstract Numerical modeling has been widely used to assess the feasibility of geothermal energy development at sites across the world, but modeling applications simulating the potential impacts on shallow hydrothermal resources and surface water are relatively scarce. In this study, we apply the MODFLOW 6 groundwater energy (GWE) code to simulate fully
Michael J. Rush, Daniel Birdsell, Lauren Foster, Renee Reichenbacher, Parker Rehmus, Tom Armstrong   +5 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du, Shunsuke Koga, Guang Yang, Saar Gill, Adam Bagg   +4 more
wiley   +1 more source