Results 51 to 60 of about 101,522 (253)

Functional genome Annotation in Bacterial infections: A Review [PDF]

Al Ameen Journal of Medical Sciences, 2021
Functional annotation provides the information of gene about its biological identity and various types of molecular function and biological role like sub-cellular location and its expression.
Sharique Ahmad, Shivani Singh, Shriya Arora, Saurabh Srivastava   +3 more
doaj  

Vader Lexicon and Support Vector Machine Algorithm to Detect Customer Sentiment Orientation

Journal of Information Systems Engineering and Business Intelligence, 2023
Background: The concept of customer orientation, which is based on a set of fundamental beliefs that prioritize the interests of the customer, requires companies to detect these interests in order to maintain a high level of quality in their products or ...
Vivine Nurcahyawati, Zuriani Mustaffa
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Fully automated landmarking and facial segmentation on 3D photographs

Scientific Reports
Three-dimensional facial stereophotogrammetry provides a detailed representation of craniofacial soft tissue without the use of ionizing radiation. While manual annotation of landmarks serves as the current gold standard for cephalometric analysis, it is
Bo Berends, Freek Bielevelt, Ruud Schreurs, Shankeeth Vinayahalingam, Thomas Maal, Guido de Jong   +5 more
doaj   +1 more source

Improving automatic GO annotation with semantic similarity

BMC Bioinformatics, 2022
Background Automatic functional annotation of proteins is an open research problem in bioinformatics. The growing number of protein entries in public databases, for example in UniProtKB, poses challenges in manual functional annotation. Manual annotation
Bishnu Sarker, Navya Khare, Marie-Dominique Devignes, Sabeur Aridhi   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Combining Manual and Automatic Annotation of a Learner Corpus [PDF]

, 2012
We present an approach to building a learner corpus of Czech, manually corrected and annotated with error tags using a complex grammar-based taxonomy of errors in spelling, morphology, morphosyntax, lexicon and style. This grammar-based annotation is supplemented by a formal classification of errors based on surface alternations.
Tomás Jelínek, Barbora Stindlová, Alexandr Rosen, Jirka Hana   +3 more
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

CODON-Software to manual curation of prokaryotic genomes.

PLoS Computational Biology, 2021
Genome annotation conceptually consists of inferring and assigning biological information to gene products. Over the years, numerous pipelines and computational tools have been developed aiming to automate this task and assist researchers in gaining ...
Bruno Merlin, Jorianne Thyeska Castro Alves, Pablo Henrique Caracciolo Gomes de Sá, Mônica Silva de Oliveira, Larissa Maranhão Dias, Gislenne da Silva Moia, Victória Cardoso Dos Santos, Adonney Allan de Oliveira Veras   +7 more
doaj   +1 more source