Results 61 to 70 of about 101,522 (253)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
ThrombUS+ Study A Annotation Manual
ThrombUS+ Study A aims to collect and create a labelled ultrasound image data set containing ultrasound image series and video clips of patients that undergo routine ultrasound scans on lower limbs, because of suspected deep vein thrombosis. The data will be used to train an AI model within ThrombUS+ project to achieve automated detection of deep vein ...
Didaskalou, Stylianos +2 more
+6 more sources
Semantic Network Manual Annotation and its Evaluation [PDF]
The Prague Bulletin of Mathematical Linguistics, 2008 Semantic Network Manual Annotation and its Evaluation The present contribution is a brief extract of (Novák, 2008). The Prague Dependency Treebank (PDT) is a valuable resource of linguistic information annotated on several layers. These layers range from morphemic to deep and they should contain all the linguistic information about the text ...
openaire +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Browser-Based GLAUx Treebank Infrastructure: Framework, Functionality, and Future
Cybernetics and Information TechnologiesThis paper presents the browser-based treebank infrastructure of GLAUx (the Greek Language AUtomated). This linguistic annotation project now has its integrated and user-friendly platform for exploring this data.
Keersmaekers Alek +3 more
doaj +1 more source
Trustability-Based Dynamic Active Learning for Crowdsourced Labelling of Emotional Audio Data
IEEE Access, 2018 The process of collecting annotated data is expensive and time-consuming. Making use of crowdsourcing instead of experts in a laboratory setting is a viable alternative to reduce these costs.
Simone Hantke +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Smart Agricultural TechnologyHigh-quality annotated data are essential for training high-performance models; therefore, the automatic annotation of instance segmentation training datasets helps improve model development efficiency and reduce development costs.
Xiaole Wang +18 more
doaj +1 more source
BMC Genomics, 2018 Background Most published genome sequences are drafts, and most are dominated by computational gene prediction. Draft genomes typically incorporate considerable sequence data that are not assigned to chromosomes, and predicted genes without quality ...
Sarah M. Pilkington +98 more
doaj +1 more source