The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Relationship between Job Fatigue and Fine Motor Skills in Cable Car Company’s Production Staff [PDF]
Background and Objective: Job fatigue is considered one of the factors affecting the performance and productivity of workers in work environments. Therefore, the objective of the present study was to investigate the relationship between job fatigue and ...
Mohammad Reza Shahahbi Kaseb +3 more
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Running your mind and life effectively when there is no life instruction manual
The problem with humans is that no life operating manual is issued at birth, leaving individuals to work out the rules for themselves. This acquisition of life skills takes time and a lot of trial and error, and many never figure it out.
Bruce Arroll, Vicki Mount
doaj
The relationships between foreign loans and development project management in the experience of the Loans Control Division of the Department of Highways in Thailand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies at Massey University, Palmerston North Campus, New Zealand [PDF]
Appendix B in Thai languageThis study is concerned with the relationships between foreign loans and development project management. The main focus of the study is to investigate factors that undermine the effectiveness and efficiency of the management of
Sukhantarat, Arunee
core
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
MANAGING A MIXED SKILL CLASS [PDF]
In a digital environment students need to manage different types of skills - cognitive, emotive and manual. When working in a mixed-skill class the differences between student abilities can disrupt the rhythm and style of the learning process and ...
Berriolo, A +2 more
core
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source
International Emigrant Selection on Occupational Skills
We present the first evidence that international emigrant selection on education and earnings materializes through occupational skills. Combining novel data from a representative Mexican task survey with rich individual-level worker data, we find that ...
Flores, Miguel +3 more
core
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source

